Blueprint vs Empirical Health
Complete Head-to-Head Comparison
Compare costs, biomarker coverage, and value to find the best blood testing service for your needs
Quick Comparison Summary
Best Value
Empirical Health
52.6 biomarkers per $100
Most Comprehensive
Empirical Health
100+ biomarkers tested
Most Tests Per Year
Empirical Health
1 tests/year
Cost & Value Comparison
Blueprint
Annual Cost$375
Tests per Year1
Total Biomarkers95+
Cost per Test$375
Empirical Health
Annual Cost$190
Tests per Year1
Total Biomarkers100+
Cost per Test$190
Service Details
| Feature | Blueprint | Empirical Health |
|---|---|---|
| Lab Locations | Labcorp (3500+) | 2200+ locations |
| Key Features | Bryan Johnson protocol, Don't Die app results, personalized longevity protocols | Personalized MD video visit included, doctor messaging, custom nutrition plan, exercise routines, mobile app |
| Notes | Basic Panel $375 (95+ biomarkers). Advanced Panel $575 (100+ biomarkers, adds thyroid, omega fatty acids, autoimmune markers). Microplastics test also available. Speed of Aging epigenetic test separate. Results in 4-6 weeks. Not available in NJ, NY, RI, HI. | $190 per test with MD video visit included. Single lab visit. HSA/FSA eligible |
Biomarker Coverage Comparison
77
Tests in Common
42
Only in Blueprint
8
Only in Empirical Health
Tests Only in Blueprint
- MCH (Mean Corpuscular Hemoglobin)(Complete Blood Count (CBC))
- MCHC (Mean Corpuscular Hemoglobin Concentration)(Complete Blood Count (CBC))
- ABO Blood Type(Complete Blood Count (CBC))
- GGT (Gamma-Glutamyl Transferase)(Liver Function)
- Free T3 (Triiodothyronine)(Thyroid Function)
- Total T4(Thyroid Function)
- Total Testosterone(Sex Hormones (Male))
- Free Testosterone(Sex Hormones (Male))
- SHBG (Sex Hormone Binding Globulin)(Sex Hormones (Male))
- Estradiol (E2)(Sex Hormones (Male))
- PSA (Prostate Specific Antigen)(Sex Hormones (Male))
- DHEA-S(Sex Hormones (Male))
- Estradiol (E2)(Sex Hormones (Female))
- Progesterone(Sex Hormones (Female))
- FSH (Follicle Stimulating Hormone)(Sex Hormones (Female))
- LH (Luteinizing Hormone)(Sex Hormones (Female))
- Prolactin(Sex Hormones (Female))
- Homocysteine(Inflammation &Immune Markers)
- Cortisol(Stress &Adrenal Function)
- Omega-3 Index / Fatty Acids(Advanced / Specialty Markers)
- Arachidonic Acid / EPA Ratio(Advanced / Specialty Markers)
- Heavy Metals - Lead(Advanced / Specialty Markers)
- Heavy Metals - Mercury(Advanced / Specialty Markers)
- IGF-1 (Insulin-like Growth Factor)(Advanced / Specialty Markers)
- ANA Screen (Antinuclear Antibodies)(Autoimmune Markers)
- ANA Titer(Autoimmune Markers)
- ANA Pattern(Autoimmune Markers)
- Rheumatoid Factor (RF)(Autoimmune Markers)
- PSA Free (Prostate Cancer)(Cancer Screening Markers)
- Zinc(Electrolytes &Minerals)
- Lipase(Liver Function)
- Leptin(Advanced / Specialty Markers)
- Omega-6 Total(Advanced / Specialty Markers)
- Linoleic Acid(Advanced / Specialty Markers)
- Arachidonic Acid(Advanced / Specialty Markers)
- Urine Albumin(Urinalysis)
- LDL Small(Lipid Panel / Cardiovascular)
- LDL Medium(Lipid Panel / Cardiovascular)
- LDL Pattern(Lipid Panel / Cardiovascular)
- LDL Peak Size(Lipid Panel / Cardiovascular)
- Omega-6/Omega-3 Ratio(Lipid Panel / Cardiovascular)
- Amylase(Pancreas &Digestive)
Tests Only in Empirical Health
- Apolipoprotein A1 (ApoA1)(Lipid Panel / Cardiovascular Health)
- Total Cholesterol/HDL Ratio(Lipid Panel / Cardiovascular Health)
- LDL/HDL Ratio(Lipid Panel / Cardiovascular Health)
- ApoB/ApoA1 Ratio(Lipid Panel / Cardiovascular Health)
- De Ritis Ratio (AST/ALT)(Liver Function)
- Albumin/Globulin Ratio (A/G)(Kidney Function)
- Band Neutrophils(Complete Blood Count (CBC))
- Reactive Lymphocytes(Complete Blood Count (CBC))
Complete Biomarker Comparison by Category
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Ready to Choose?
Based on this comparison, make an informed decision about your blood testing provider
Frequently Asked Questions
Which provider is better:Blueprint or Empirical Health?
Empirical Health provides better value with 52.6 biomarkers per $100 spent, offering more comprehensive coverage for your investment.
However, the best choice depends on your specific health goals, budget, and which biomarkers are most important for your situation.
How much do Blueprint and Empirical Health cost per year?
Blueprint costs $375 per year for 1,
while Empirical Health costs $190 per year for 1.
The cost per test is $375
for Blueprint and $190
for Empirical Health.
What biomarkers does Blueprint test that Empirical Health doesn't?
Blueprint includes 42 unique biomarkers not found in Empirical Health's panel.
These include MCH (Mean Corpuscular Hemoglobin), MCHC (Mean Corpuscular Hemoglobin Concentration), ABO Blood Type, and others.
Can I use insurance with Blueprint or Empirical Health?
Both Blueprint and Empirical Health are direct-to-consumer services that typically don't accept insurance.
However, you may be able to submit receipts to your insurance for reimbursement if you have out-of-network benefits,
or use HSA/FSA funds for payment. Check with your insurance provider and the testing companies for specific policies.
How often should I get blood work done?
Most health optimization experts recommend testing 2-4 times per year to establish baselines and track trends.
Blueprint includes 1 in their annual membership,
while Empirical Health includes 1.
More frequent testing allows you to track the effectiveness of interventions and catch changes early.
Where can I get blood drawn for these tests?
Blueprint uses Labcorp (3500+),
while Empirical Health uses 2200+ locations.
Both typically have thousands of collection centers nationwide. You'll schedule your blood draw through their platform after ordering.
Frequently Asked Questions
Which is cheaper, Blueprint or Empirical Health?
Empirical Health is cheaper at $190/year compared to Blueprint at $375/year.
Which tests more biomarkers, Blueprint or Empirical Health?
Blueprint tests 95+ biomarkers while Empirical Health tests 100+ biomarkers.
What is Blueprint best for?
Blueprint offers 95+ biomarkers for $375/year with 1 test(s) per year. Key features include:Bryan Johnson protocol, Don't Die app results, personalized longevity protocols
What is Empirical Health best for?
Empirical Health offers 100+ biomarkers for $190/year with 1 test(s) per year. Key features include:Personalized MD video visit included, doctor messaging, custom nutrition plan, exercise routines, mobile app
Which offers better value, Blueprint or Empirical Health?
Empirical Health offers better value with approximately 52.6 biomarkers per $100 spent, compared to Blueprint's 25.3 biomarkers per $100.