Expert Articles
26 articles from functional medicine doctors and longevity researchers on optimal biomarker ranges.
Nucleus Health · Nucleus
Comprehensive guide to Peter Attia's blood test recommendations including his optimal ranges for longevity
Key Optimal Ranges
ApoB:30-40 mg/dL (ceiling 60 mg/dL), HbA1c:<5.5%
ApoBLp(a)LDL-POGTTInsulinHbA1c
Dr. Mark Hyman · Dr. Hyman Blog
Essential blood tests and optimal ranges from a functional medicine perspective
Key Optimal Ranges
Fasting Glucose:<85 mg/dL, Fasting Insulin:2-5 mIU/dL, HbA1c:<5.5%
Fasting GlucoseFasting InsulinHbA1cLipids
Chris Kresser · Revolution Health Radio
Functional medicine approach to cholesterol including LDL particle number and inflammation markers
Key Optimal Ranges
Total Cholesterol/HDL Ratio:<3.5, HDL:>60 mg/dL
LDL-CLDL-PApoBHDLTriglyceridesCRP
Chris Kresser · Revolution Health Radio
Chris Kresser discusses essential lab tests and what they reveal about root causes of health problems
Key Optimal Ranges
HbA1c:4.6-5.3%, Uric Acid:<7-8 mg/dL
Fasting GlucoseFasting InsulinTSHFree T3Free T4LipidsCRP
Ben Greenfield · Ben Greenfield Life
Deep dive into cortisol physiology and optimal ranges for health and longevity
Key Optimal Ranges
Morning Cortisol:14-18 μg/dL, DHEA:supports testosterone production
CortisolDHEATestosteroneProgesterone
Ben Greenfield · Ben Greenfield Life
Advanced discussion of cortisol testing and comprehensive hormone panels
Key Optimal Ranges
Custom ranges based on individual baselines and symptoms
CortisolDHEAACTHHormone Metabolites
Dr. Rhonda Patrick · NL Physio
Expert advice on vitamin D3 supplementation and optimal blood levels
Key Optimal Ranges
Vitamin D:40-60 ng/mL
Vitamin D25-hydroxyvitamin D
Dr. Rhonda Patrick · FoundMyFitness
Discussion of vitamin D deficiency risks and omega-3 benefits for longevity
Key Optimal Ranges
Omega-3 Index:>8%, Vitamin D:40-60 ng/mL
Vitamin DOmega-3 IndexEPADHA
Optimal DX · Optimal DX Blog
Comprehensive guide to homocysteine optimal ranges for cardiovascular health
Key Optimal Ranges
Homocysteine:<7 μmol/L (optimal), <10.5 μmol/L (acceptable)
Homocysteine
Optimal DX · Optimal DX Blog
Understanding hs-CRP as a marker of inflammation and cardiovascular risk
Key Optimal Ranges
hs-CRP:<0.5 mg/L (optimal), <1 mg/L (low risk)
hs-CRP
Optimal DX · Optimal DX Blog
GGT as a metabolic marker beyond liver health including insulin resistance risk
Key Optimal Ranges
GGT:<18 U/L (men), <9 U/L (women), AST:<35 U/L, ALT:<33 U/L (men), <25 U/L (women)
GGTALTAST
Rupa Health · Rupa Health Blog
Comprehensive guide to thyroid testing from functional medicine perspective
Key Optimal Ranges
TSH:0.5-2.5 mIU/L (optimal vs 0.45-4.12 standard)
TSHFree T3Free T4Reverse T3TPO Antibodies
Healthline · Healthline
Evidence-based guide to optimal thyroid levels for longevity and health
Key Optimal Ranges
TSH:0.5-2.5 mIU/L, 60-80th percentile associated with lowest mortality
TSHFree T3Free T4
Center for Hormones &Wellness · Hormone Wellness
Understanding the difference between normal and optimal testosterone levels
Key Optimal Ranges
Men:>600 ng/dL for lower mortality risk, Women:10-55 ng/dL (premenopausal)
Total TestosteroneFree Testosterone
Rupa Health · Rupa Health Blog
Comprehensive guide to understanding and interpreting liver enzyme tests
Key Optimal Ranges
ALT:19-25 U/L (women), 29-33 U/L (men), AST:<35 U/L
ALTASTALPGGT
Nia Health · Nia Health Blog
Summary of key biomarkers Peter Attia tracks in his book Outlive
Key Optimal Ranges
ApoB:<60 mg/dL, VO2 Max:maximize for age, HbA1c:<5.5%
ApoBLp(a)LDL-PVO2 MaxHbA1cInsulin
I Won't Die · I Won't Die Blog
Inside look at Bryan Johnson's comprehensive bloodwork and optimal ranges
Key Optimal Ranges
Top 1% results across multiple biomarkers, Biological age:0.64 speed of aging
HbA1cCystatin CTestosteroneEstradiolCRPLipidsIGF-1
My Vital Metrics · My Vital Metrics Blog
Comprehensive guide to blood tests that predict longevity and healthspan
Key Optimal Ranges
Multi-marker approach for comprehensive longevity assessment
ApoBhs-CRPHomocysteineHbA1cVitamin DOmega-3 Index
Chris Kresser · Chris Kresser Blog
Root cause approach to diabetes with focus on insulin and glucose regulation
Key Optimal Ranges
Emphasis on early intervention before diabetes develops
Fasting InsulinFasting GlucoseHbA1cFructosamineTriglycerides
Dr. Hagmeyer · Dr. Hagmeyer Blog
Comprehensive guide to inflammation markers and their optimal ranges
Key Optimal Ranges
hs-CRP:<1 mg/L, Homocysteine:5-7.2 μmol/L, Ferritin:context-dependent
CRPESRHomocysteineFerritinFibrinogen
DNA Care · DNA Care Blog
Understanding hs-CRP as early marker of inflammation and cardiovascular disease
Key Optimal Ranges
hs-CRP:<0.55 mg/L (men), <1 mg/L (women)
hs-CRP
Dr. Mark Hyman · Dr. Hyman Blog
Evidence-based approach to reversing diabetes through optimal metabolic markers
Key Optimal Ranges
Fasting glucose:<80 mg/dL, Never above 110-120 mg/dL post-meal
Fasting GlucoseFasting InsulinPost-prandial Glucose &Insulin
Optimal DX · Optimal DX
Comprehensive database of functional medicine optimal ranges vs standard ranges
Key Optimal Ranges
Tighter ranges than conventional labs for early dysfunction detection
Multiple biomarkers across all systems
Dr. Mark Hyman · Dr. Hyman Blog
Focus on insulin testing as critical missing marker in standard panels
Key Optimal Ranges
Fasting insulin:<10 mIU/dL, optimal:2-5 mIU/dL
Fasting InsulinHOMA-IR
Ben Greenfield · Ben Greenfield Life
Evidence-based strategies for optimizing testosterone through lifestyle
Key Optimal Ranges
Natural optimization targeting >600 ng/dL for men
TestosteroneDHEAEstradiolSHBG
Nia Health · Nia Health Blog
Understanding VO2 max as a key longevity biomarker discussed by Huberman
Key Optimal Ranges
Top quartile for age associated with 5x lower mortality risk
VO2 MaxLactate Threshold
