Best Hormone Tests in 2026
Hormone optimization, particularly testosterone replacement therapy (TRT), has moved from specialty clinics to telemedicine platforms. Men can now get diagnosed, prescribed, and monitored without leaving home. We compared six TRT providers on pricing transparency, medication options, lab monitoring, and clinical quality. Monthly costs range from $99 to $225, with significant variation in what's included. Some bundle everything while others charge separately for medications, labs, and consultations. Beyond cost, we evaluated protocol sophistication since cookie-cutter approaches often produce suboptimal results or unwanted side effects. This guide helps you find a provider that balances convenience with proper medical oversight, avoiding both low-quality pill mills and unnecessarily expensive concierge services.
Quick Comparison
At-a-glance comparison of our top picks. Updated Jan 2026
| Rank | Provider | Price | Best For |
|---|---|---|---|
| 1 | Marek Health | $225/mo | Advanced protocols with expert oversight |
| 2 | Defy Medical | $99/mo | Established clinic with nationwide access |
| 3 | TRT Nation | $99/mo | Budget-friendly all-inclusive TRT |
| 4 | Hone Health | $149/mo | Modern app experience with at-home labs |
| 5 | Peter Uncaged MD | $139/mo | Peptides and advanced hormone protocols |
| 6 | Fountain TRT | $199/mo | Simple all-inclusive testosterone therapy |
Top Picks
Detailed breakdown of each recommended option with pros, cons, and who it's best for.
Marek Health
Defy Medical
TRT Nation
Hone Health
Peter Uncaged MD
Fountain TRT
How We Chose These Picks
Frequently Asked Questions
What's included in TRT clinic monthly fees?
This varies dramatically. Some all-inclusive services bundle consultation, labs, and medications. Others charge a low base fee then add on medication costs, lab fees, and consultation charges. Always ask for total year-one cost including initial consultation, ongoing visits, quarterly labs, and all medications. The cheapest monthly fee often isn't the cheapest total cost.
How do I know if I actually need TRT?
Legitimate clinics require bloodwork showing low testosterone (typically below 300 ng/dL total testosterone) plus symptoms like fatigue, low libido, muscle loss, or depression. Be wary of clinics that prescribe based on symptoms alone or treat men with normal levels. Some symptoms of low T overlap with other treatable conditions. Get comprehensive labs before committing.
Is online TRT legal and safe?
Yes, telemedicine TRT is legal throughout the US when properly conducted. Clinics employ licensed physicians who prescribe scheduled medications through licensed pharmacies. Safety comes from proper monitoring including regular bloodwork to check hematocrit, PSA, and hormone levels. The main risk isn't legality but quality. Some clinics provide inadequate monitoring or inexperienced prescribers.
What medications do TRT clinics typically prescribe?
Testosterone cypionate or enanthate injections are standard. Quality clinics also offer HCG to maintain fertility and testicular function, aromatase inhibitors if estrogen rises too high, and occasionally alternatives like clomiphene for men wanting to avoid exogenous testosterone. Some now offer peptides and growth hormone secretagogues, though these are less established.
How long does it take to feel results from TRT?
Energy and mood improvements often appear within 2-4 weeks. Libido changes typically follow in 3-6 weeks. Body composition changes (muscle gain, fat loss) require 3-6 months of consistent therapy combined with exercise. Full optimization, where bloodwork stabilizes and dose adjustments settle, usually takes 3-6 months. Be skeptical of clinics promising immediate dramatic results.
Ready to Get Started?
Compare all options and find the best fit for your health goals.
View All Hormone Optimization OptionsImportant Disclaimer
This comparison is for informational purposes only and is not medical advice. Prices are based on January 2026 data and may vary. Consult with a healthcare provider before making health-related decisions.