DNA & Genetic Testing 2026

Compare DNA testing services from whole genome sequencing to SNP arrays. Health reports, ancestry, carrier screening, pharmacogenomics, and privacy policies compared.

8 Services Compared$99–$399 Price RangeAt-Home CollectionHSA/FSA Eligible
See Our Top Picks →
Most Health Reports
SelfDecode
1500+ reports, AI recommendations
Most Complete Data
Nebula Genomics
Whole genome, 6B positions
FDA Approved
23andMe
Only FDA-approved DTC test

Understanding DNA Testing Options

DNA tests fall into two main categories:SNP arrays (~600K positions, $99-199) and whole genome sequencing (6 billion positions, $299-499). SNP tests cover the most clinically relevant variants and are sufficient for most health insights. Whole genome sequencing provides complete data but requires more interpretation. Many services now accept raw data uploads, letting you get multiple analyses from one test.

Pricing & Subscriptions

Complete cost breakdown including test pricing and ongoing subscription fees. Updated Jan 2026

ProviderBase PriceSubscriptionTest TypeTurnaround
Nebula Genomics$99$19.99/monthlyWhole Genome12-14 weeks
SelfDecode$199$99/annualSNP Array + AI Imputation4-6 weeks
23andMe$199NoneSNP Array3-4 weeks
Sequencing.com$399NoneWhole Genome 30x8-12 weeks
InsideTracker$249NoneSNP Array + Blood7-10 days
MyToolbox Genomics$199NoneSNP Array + Epigenetics4-6 weeks
Dante Labs$299NoneWhole Genome 30x8-10 weeks
Nucleus Genomics$399NoneWhole Genome 30x6-8 weeks

Testing Coverage

Compare what each test analyzes - from targeted SNPs to full genome sequencing.

ProviderPositions TestedHealth ReportsAncestryRaw Data
Nebula Genomics6.0B340+YesYes
SelfDecode8000001500+YesYes
23andMe600000150+YesYes
Sequencing.com6.0BVaries by appOptionalYes
InsideTrackerUnknownLimited geneticsNoNo
MyToolbox GenomicsUnknown115YesYes
Dante Labs6.0B150+YesYes
Nucleus Genomics6.0B20+ polygenic scoresYesYes

Features & Privacy

Compare carrier screening, pharmacogenomics, FDA approval, and privacy protections.

ProviderCarrier ScreeningPharmacogenomicsFDA ApprovedPrivacy
Nebula GenomicsYesYesNoBlockchain privacy partnership with Oasis Labs
SelfDecodeYesYes (add-on $99)NoHIPAA compliant
23andMeYesYesYesOpt-out of research
Sequencing.comVia appsVia appsNoPrivacy Forever guarantee
InsideTrackerNoNoNoHIPAA compliant
MyToolbox GenomicsNoNoNoStandard data protection
Dante LabsYesYesNoGDPR compliant
Nucleus GenomicsYesNoNoNo third-party sharing

Provider Details

In-depth look at each DNA testing service including features, methodology, and who it's best for.

Nebula Genomics

Weekly report updates|Oral microbiome analysis|Genome exploration tools|Upload existing DNA data free
$99 + $19.99/monthly

Best For

Full genome sequencing (6B positions vs 600K SNPs)

Key Features

Weekly report updates|Oral microbiome analysis|Genome exploration tools|Upload existing DNA data free

Whole Genome12-14 weeksSalivaRaw data download

SelfDecode

AI-powered health recommendations|Personalized supplement suggestions|Lifestyle...
$199 + $99/annual

Best For

Health recommendations with supplement suggestions

Key Features

AI-powered health recommendations|Personalized supplement suggestions|Lifestyle optimization|Family plan available

SNP Array + AI Imputation4-6 weeksSalivaRaw data download

23andMe

Only FDA-approved DTC DNA test|Large relative database|Detailed ancestry regions (1500+)|Traits reports
$199

Best For

FDA-approved health reports and finding relatives

Key Features

Only FDA-approved DTC DNA test|Large relative database|Detailed ancestry regions (1500+)|Traits reports

SNP Array3-4 weeksSalivaFDA ApprovedRaw data download

Sequencing.com

App marketplace with 50+ analysis tools|Upload competitor results|Lifetime data storage|HSA/FSA eligible
$399

Best For

Flexibility with third-party analysis apps

Key Features

App marketplace with 50+ analysis tools|Upload competitor results|Lifetime data storage|HSA/FSA eligible

Whole Genome 30x8-12 weeksSalivaRaw data download

InsideTracker

Combines DNA with blood biomarkers|Personalized action plans|InnerAge calculation|Fastest results
$249

Best For

Integrating genetic and blood data for optimization

Key Features

Combines DNA with blood biomarkers|Personalized action plans|InnerAge calculation|Fastest results

SNP Array + Blood7-10 daysSaliva + Blood

MyToolbox Genomics

No subscription required|Epigenetic age testing|Custom meal plans|Training...
$199

Best For

Budget-conscious users wanting no subscription

Key Features

No subscription required|Epigenetic age testing|Custom meal plans|Training recommendations|Vitamin suggestions

SNP Array + Epigenetics4-6 weeksSalivaRaw data download

Dante Labs

European-based WGS|Predisposition reports|Clinical-grade sequencing|No subscription
$299

Best For

European users or those preferring EU data storage

Key Features

European-based WGS|Predisposition reports|Clinical-grade sequencing|No subscription

Whole Genome 30x8-10 weeksSalivaRaw data download

Nucleus Genomics

Polygenic risk scores for diseases|Clean privacy model|Founded by genomics experts|Illumina sequencing
$399

Best For

Disease risk assessment via polygenic scores

Key Features

Polygenic risk scores for diseases|Clean privacy model|Founded by genomics experts|Illumina sequencing

Whole Genome 30x6-8 weeksSalivaRaw data download

Frequently Asked Questions

What is the difference between SNP testing and whole genome sequencing?

SNP (Single Nucleotide Polymorphism) testing analyzes around 600,000 specific genetic markers that vary between people. Whole genome sequencing (WGS) reads all 6 billion base pairs of your DNA, providing 10,000x more data. SNP tests cost $99-199 while WGS costs $299-499. WGS is more comprehensive but SNP tests cover the most clinically relevant variants.

Which DNA test is best for health reports?

SelfDecode offers 1500+ health reports with AI-powered recommendations. Nebula Genomics provides 340+ trait reports with weekly updates. 23andMe is the only FDA-approved consumer DNA test for health, offering 55+ reports. For the most actionable health insights, SelfDecode leads;for FDA validation, 23andMe is the safest choice.

Is 23andMe safe after their bankruptcy?

23andMe filed for bankruptcy in March 2025 and was subsequently sold. The company continues to operate under new ownership. Your data privacy depends on the new ownership policies. If privacy is a concern, consider services like Nebula Genomics (blockchain privacy) or Sequencing.com (Privacy Forever guarantee).

Can I upload my existing DNA data to other services?

Yes, many services accept raw DNA data from 23andMe, AncestryDNA, and others. SelfDecode charges $99/year for upload analysis. Nebula Genomics offers free uploads with limited reports. Sequencing.com accepts uploads and provides access to their app marketplace. This lets you get more value from a single DNA test.

What health conditions can DNA tests detect?

DNA tests can identify genetic risk for conditions like heart disease, Alzheimer's, certain cancers, and metabolic disorders. They also reveal carrier status for inherited conditions (important for family planning), pharmacogenomics (how you metabolize medications), and traits affecting nutrition and fitness. Results show genetic predisposition, not diagnosis.

How long do DNA test results take?

Turnaround varies significantly:23andMe takes 3-4 weeks, SelfDecode 4-6 weeks, and whole genome sequencing services like Nebula take 12-14 weeks. InsideTracker offers the fastest results at 7-10 days but combines DNA with blood testing.

Are DNA tests HSA/FSA eligible?

Many DNA tests qualify for HSA/FSA payment. Sequencing.com explicitly advertises HSA/FSA eligibility. Check with your account administrator, as eligibility can depend on the specific test and whether it has a health component versus ancestry-only.

What is pharmacogenomics testing?

Pharmacogenomics (PGx) testing analyzes genes that affect drug metabolism, helping predict how you'll respond to medications. This can optimize drug selection and dosing for antidepressants, blood thinners, pain medications, and more. SelfDecode offers PGx as a $99 add-on;23andMe includes basic PGx in premium plans.

Combine Genetics with Blood Testing

Get the full picture by combining genetic insights with real-time blood biomarker data.

Compare Blood Test Services

Important Disclaimer

This comparison is for informational purposes only and is not medical advice. Genetic test results show predisposition, not diagnosis. Results should be discussed with a healthcare provider or genetic counselor. Prices are based on January 2026 data and may vary. Privacy policies change;verify current terms before purchasing.