Biological Age & Longevity Testing 2026
Compare biological age testing services using epigenetic clocks, glycan analysis, and blood biomarkers. Find out how old your body really is and track your longevity interventions.
Understanding Biological Age Testing
Biological age tests measure how old your body is at the cellular level, which can differ from your chronological (calendar) age. Most tests analyze epigenetic markers (DNA methylation patterns) that change with aging. A younger biological age correlates with better health outcomes and longevity. These tests help track whether your lifestyle interventions are actually slowing or reversing aging.
Pricing & Options
Complete cost breakdown including test pricing, retesting discounts, and subscription options. Updated Jan 2026
| Provider | Test Name | Price | Subscription | Retest Discount |
|---|---|---|---|---|
| TruAge Test | $499 | $998/yr (4 tests at $249.50 each, currently a 50% off promo) | Yes | |
| Index | $299 | None | No | |
| GlycanAge | $499 | Yes ($449/yr annual, $424 bi-annual) | No | |
| myDNAge | $299 | None | No | |
| InnerAge 2.0 | $249 | Yes | Yes | |
| TallyAge Test | $249 | $129/mo membership | No | |
| Humanity App | $180 | $180/yr Pro | No | |
| NOVOS Age | $349 | None | No | |
| GrimAge Test | $325 | $150/mo (Advanced plan, list $350) or $50/mo (Longevity Biomarker plan, list $125) | No |
Testing Methodology
Compare the science behind each test - epigenetic clocks, glycan analysis, or blood biomarkers.
| Provider | Methodology | Clock/Algorithm | Biomarkers | Sample Type |
|---|---|---|---|---|
| TruDiagnostic | Epigenetic | OMICmAge, DunedinPACE, SYMPHONYAge | 75+ | Blood |
| Elysium Health | Epigenetic | APEX (Morgan Levine) | DNA methylation | Saliva |
| GlycanAge | Glycan | IgG Glycome Analysis | 24 IgG glycans | Blood (finger prick) |
| myDNAge | Epigenetic | Horvath Clock (licensed) | DNA methylation (2000+ loci) | Blood (finger prick) |
| InsideTracker | Blood Biomarker | Proprietary algorithm | 17 (men) / 13 (women) | Blood (lab draw or mobile) |
| Tally Health | Epigenetic | TallyAge (proprietary) | DNA methylation | Cheek swab |
| Humanity | Wearable + Blood | Proprietary algorithm | Wearable metrics + optional blood biomarkers | App (Apple Health/wearables) |
| NOVOS | Epigenetic | DunedinPACE, Organ Age algorithms | 150+ biomarkers | Blood (finger prick) |
| Clock Foundation | Epigenetic | GrimAge, PhenoAge (Steve Horvath) | DNA methylation | Blood (finger prick) |
Accuracy & Actionability
Compare validation, systems tracked, and how actionable the results are.
| Provider | Systems Tracked | Validation | Actionability | Recommendations |
|---|---|---|---|---|
| TruDiagnostic | 11 organ systems | 50+ peer-reviewed publications, 98% test-retest reproducibility | ★★★★★ | Yes |
| Elysium Health | 9 systems | Nature Aging publication | ★★★★☆ | Yes (100+) |
| GlycanAge | Immune/Inflammation | +/-1 year in-day measurement precision;250,000+ samples analyzed | ★★★★★ | Yes (1-on-1 expert consultation) |
| myDNAge | Overall biological age | Original Horvath clock validation | ★★★☆☆ | Limited |
| InsideTracker | Blood biomarkers | 60% improve on retest | ★★★★☆ | Yes (action plan) |
| Tally Health | Overall biological age + pace of aging | Trained on 8,000+ adult cheek-swab dataset;20k+ tests performed | ★★★★☆ | Yes (health coaching) |
| Humanity | Rate of aging tracking | Nature publication | ★★★★☆ | Yes (personalized insights) |
| NOVOS | 11 organ systems | DunedinPACE validated in 45+ studies (ICC >0.96) | ★★★★★ | Yes (detailed report) |
| Clock Foundation | Mortality/morbidity prediction | Gold standard in research | ★★★★★ | Yes |
Provider Details
In-depth look at each biological age testing service including features, methodology, and who it's best for.
TruDiagnostic - TruAge Test
Key Features
75+ biomarkers across 11 organ systems, DunedinPACE pace of aging, 11 organ system scores, telomere length, immune cell composition
Details
$499 single test. Annual subscription $249.50 per test for 4 tests ($998/yr), but note this is currently a limited-time 50% off promo against a $499/test list, so the durable annual figure is nearer $1,996. Renamed from TruAge Complete to TruAge Test;sibling products TruHealth $499 and a TruAge + TruHealth combination kit $849. Now measures 1,000,000+ methylation sites and names a DeepStrataAge clock alongside OMICmAge, SYMPHONYAge and DunedinPACE. Owned by Infinite Epigenetics, which also acquired Tally Health in April 2026 - the two are corporate siblings.
Elysium Health - Index
Key Features
Developed with Yale researcher Morgan Levine, custom Illumina chip, brain/heart/metabolic/immune/inflammation/kidney/liver/hormone/blood system scores
Details
$299 one-time purchase with NO subscription offered - Elysium's product data confirms no selling plans exist. The previously recorded '$499 single test or $299 with subscription'described a two-tier structure that does not exist on either half. Saliva-based epigenetic test using the APEX algorithm developed with Morgan Levine at Yale and published in Nature Aging. Reports biological age, cumulative rate of aging and 9 system age scores, with 100+ lifestyle recommendations and free enrolment in the Aging Research Center longitudinal study. Results in about 6 weeks.
GlycanAge - GlycanAge
Key Features
Only glycan-based test, responds to lifestyle changes faster than epigenetic clocks, expert consultation included, less than 1% error margin
Details
$499 one-off purchase, up from $348. Subscriptions now exist where we previously recorded none:annual $449 (10% saving) and bi-annual $424 (15%), both cancel-anytime. Two-test bundle $898, list $998 - the previously stored $599 retest figure is obsolete. Measures IgG N-glycosylation rather than methylation, so it responds to lifestyle change in weeks rather than months, which is its main differentiator. Includes a 1:1 results interpretation call available for 60 days after results.
myDNAge - myDNAge
Key Features
Exclusively licensed Horvath epigenetic clock (original 353 CpG sites), proprietary SWARM technology analyzing 2000+ methylation loci, new Epi-Metabolic Index plus APOE and MTHFR, at-home blood collection
Details
$299 at-home blood kit using two to three drops via lancet. Uses the original Horvath clock under exclusive licence, with SWARM technology extending it across 2,000+ methylation loci. The report now adds an Epi-Metabolic Index for metabolic disease risk plus APOE and MTHFR results. The urine kit is no longer sold - only the blood kit remains, so the previous 'blood or urine'framing is out of date. Results in 4-6 weeks. Operated by Epimorphy LLC.
InsideTracker - InnerAge 2.0
Key Features
Blood biomarker-based (not epigenetic), integrates with DNA and wearables, personalized action plans, tracks improvement over time
Details
Different approach using blood biomarkers vs DNA methylation. Tiered pricing:$99 analysis-only (use existing labs), $249 with lab blood draw, $348 with mobile blood draw. Best for those who want actionable blood test optimization alongside biological age.
Tally Health - TallyAge Test
Key Features
David Sinclair co-founded, trained on largest cheek-swab DNA methylation dataset (8000+ adults), easy cheek swab collection, health coach consultations, personalized supplement recommendations, ongoing tracking
Details
Founded by David Sinclair. Single TallyAge test $249 one-time;membership $129/mo includes a test every 6 months, personalised action plans, Daily Vitality supplements and 15% off add-on supplements. Cheek swab, results in 4-6 weeks. ACQUIRED by Infinite Epigenetics - TruDiagnostic's parent - in April 2026, so Tally Health and TruDiagnostic are now corporate siblings rather than independent options. Operates as a standalone brand with CEO Melanie Goldey. The previously recorded $234 member retest price could not be reproduced anywhere on the site.
Humanity - Humanity App
Key Features
Uses Apple Health and wearable data, optional blood test integration via AI, tracks rate of aging, habit tracking, no physical sample for base features
Details
UNVERIFIED PRICING:Humanity no longer publishes a price anywhere. humanity.health/pricing returns 404 and no dollar figure appears on the marketing site;the App Store listing shows in-app purchases without amounts. The $180/yr recorded here traces only to third-party aggregators and could not be confirmed first-party in the August 2026 refresh - treat it as an estimate. App renamed to HUMANITY - AI Health Coach, positioning shifted toward generative AI and 'Large Biological Models', claiming 200k+ users. Blood-marker upload via its Nature-published blood age model is still described as a feature.
NOVOS - NOVOS Age
Key Features
Only test with both DunedinPACE (Columbia/Duke) and Organ Age (Yale) clocks, 150+ biomarkers analyzed, 11 organ-specific biological ages, personalized longevity advice
Details
$349 for a single kit, or $299 per kit for two or more. Explicitly a one-time purchase with no membership. DunedinPACE from Columbia and Duke plus Organ Age from Yale, covering 11 organ systems and telomere length across 150+ biomarkers and 850,000 methylation sites on the MethylationEPIC array. Finger-prick blood, 55-page report plus a free AI Longevity Coach, results in 2-4 weeks. Ships within the United States and Canada only.
Clock Foundation - GrimAge Test
Key Features
Created by Steve Horvath (invented epigenetic clocks), GrimAge predicts mortality risk, PhenoAge kit available separately ($95, list $125), analysis-only options for existing data (GrimAge $45, PhenoAge $29), nonprofit
Details
The original - Steve Horvath invented the epigenetic clock in 2013, and GrimAge is considered the gold standard in longevity research for mortality prediction. GrimAge kit $325 (list $375);international kit $349. PhenoAge kit is now $95, up from the $75 previously recorded. Analysis-only options for existing data:GrimAge $45, PhenoAge $29. Monthly bundles at $150/mo (GrimAge + PhenoAge + wearables) and $50/mo (PhenoAge + wearables). Finger-prick blood, results in 2-3 weeks. 50+ clinical partners and 15,000+ tests performed.
Frequently Asked Questions
What is biological age testing?
Biological age testing measures how old your body is at the cellular level, which can differ from your chronological age. Most tests use epigenetic markers (DNA methylation patterns) that change with aging. A 50-year-old with healthy habits might have a biological age of 45, while someone the same age with poor health could test at 55+.
What is an epigenetic clock?
An epigenetic clock is an algorithm that analyzes DNA methylation patterns to estimate biological age. The original Horvath clock (2013) set the standard, measuring ~350 CpG sites. Newer clocks like DunedinPACE measure the rate of aging rather than just current biological age, while OMICmAge and APEX incorporate additional aging markers for improved accuracy.
Which biological age test is most accurate?
TruDiagnostic's TruAge is considered the most comprehensive, using multiple algorithms (OMICmAge, DunedinPACE, SYMPHONYAge) and measuring 75+ biomarkers across 11 organ systems. Elysium Index uses the APEX algorithm developed with Yale researcher Morgan Levine and is validated in Nature Aging. GlycanAge uses a different approach (glycan analysis) that responds faster to lifestyle changes.
How often should I test my biological age?
Most providers recommend retesting every 6-12 months to track changes from lifestyle interventions. Epigenetic age changes slowly (months to years), while glycan-based tests like GlycanAge may show changes in weeks. Testing too frequently wastes money as meaningful changes take time to manifest.
Can I lower my biological age?
Yes, research shows biological age can be reduced through lifestyle changes. Studies have demonstrated improvements from exercise, diet optimization, stress reduction, and quality sleep. Some interventions like caloric restriction and specific supplements have shown measurable reductions in epigenetic age markers. See YouBoost for evidence ratings on specific interventions.
What's the difference between epigenetic and blood biomarker tests?
Epigenetic tests (TruAge, Elysium, myDNAge) analyze DNA methylation patterns that correlate with aging at a fundamental level. Blood biomarker tests (InsideTracker InnerAge) measure traditional markers like glucose, cholesterol, and inflammation that are associated with aging. Glycan tests (GlycanAge) measure sugar molecules attached to antibodies. Each approach has tradeoffs in depth, actionability, and responsiveness to interventions.
Do I need a doctor to order a biological age test?
No, most biological age tests are available direct-to-consumer without a prescription. You order online, receive a collection kit at home, and mail back your sample. Some tests use a simple finger prick (myDNAge, NOVOS), cheek swab (Tally Health), or saliva sample (Elysium, EpiAging). Tests requiring a full blood draw typically partner with labs like Quest for convenient sample collection.
What is DunedinPACE and why does it matter?
DunedinPACE (Pace of Aging Computed from the Epigenome) measures how fast you're aging right now, rather than just your current biological age. Developed from the Dunedin longitudinal study tracking 1,000+ people from birth, it shows whether you're aging faster or slower than 1 year per calendar year. A score of 1.0 means normal aging;below 1.0 means slower aging. This metric is better for tracking intervention effectiveness.
Are biological age tests covered by insurance or HSA/FSA?
Biological age tests are typically not covered by health insurance as they're considered preventive/wellness testing. However, many providers accept HSA (Health Savings Account) and FSA (Flexible Spending Account) funds, making them eligible health expenses. TruDiagnostic, Elysium, and several others specifically advertise HSA/FSA eligibility. Check with your account administrator to confirm.
What interventions have been shown to lower biological age?
Research has demonstrated biological age reductions from:regular exercise (especially HIIT and resistance training), caloric restriction or time-restricted eating, quality sleep (7-9 hours), stress reduction practices like meditation, and specific supplements (Vitamin D, omega-3s, NAD+ precursors). The Horvath lab showed an 8-week lifestyle intervention reduced epigenetic age by 3.23 years. GlycanAge responds fastest to changes, showing improvements in weeks. Browse evidence-rated interventions →
Track Your Complete Health Picture
Combine biological age testing with comprehensive blood biomarker analysis for full longevity optimization.
Compare Blood Test ServicesImportant Disclaimer
This comparison is for informational purposes only and is not medical advice. Biological age testing is an emerging field and results should be interpreted with appropriate skepticism. Prices are based on January 2026 data and may vary. Consult with a healthcare provider before making health decisions based on these tests.