Total Cholesterol/HDL Ratio
The total cholesterol to HDL ratio compares overall cholesterol burden with protective HDL and is used as a summary cardiovascular risk index. Lower ratios suggest a healthier lipid balance, while values above 5 indicate elevated risk. The ratio is part of several cardiovascular risk calculators and can be followed to monitor treatment response alongside LDL or ApoB.
7 of 22 providers
Lipid Panel / Cardiovascular Health
<4.5 optimal, <5.0 acceptable
What is Total Cholesterol/HDL Ratio?
The total cholesterol to HDL ratio compares overall cholesterol burden with protective HDL and is used as a summary cardiovascular risk index. Lower ratios suggest a healthier lipid balance, while values above 5 indicate elevated risk. The ratio is part of several cardiovascular risk calculators and can be followed to monitor treatment response alongside LDL or ApoB.
Why It Matters
A key indicator of cardiovascular disease risk. Lower ratios indicate better heart health because HDL helps remove cholesterol from arteries. Optimal is below 3.5;above 5.0 indicates elevated risk.
Which Providers Test Total Cholesterol/HDL Ratio?
Full Provider Comparison
| Provider | Includes | Annual Cost | Biomarkers |
|---|---|---|---|
 Superpower | ✓ | $199 | 100+ (150 with ratios) |
 WHOOP Advanced Labs | ✓ | $349 | 65 |
 Labcorp OnDemand | — | $398 | 40+ |
| — | $486 | 40+ | |
| — | $449 | 288 | |
| ✓ | $349 | 100+ | |
| — | $829 | 54 | |
 Function Health | — | $365 | 160+ |
| — | $250 | 65 | |
| — | $495 | 80+ | |
| — | $895 | 100+ | |
| — | $1950 | 130+ | |
| — | $375 | 95+ | |
| — | $Varies | 75+ | |
| ✓ | $190 | 100+ | |
| ✓ | $99 | 50 | |
| — | $124 | 60 | |
| ✓ | $349 | 130+ | |
| — | $349 | 80+ | |
| — | $375 | 85 | |
| — | $700 | 128 | |
| ✓ | $99 | 100+ |
Frequently Asked Questions
What is Total Cholesterol/HDL Ratio?
The total cholesterol to HDL ratio compares overall cholesterol burden with protective HDL and is used as a summary cardiovascular risk index. Lower ratios suggest a healthier lipid balance, while values above 5 indicate elevated risk. The ratio is part of several cardiovascular risk calculators and can be followed to monitor treatment response alongside LDL or ApoB.
What is the optimal range for Total Cholesterol/HDL Ratio?
The standard reference range for Total Cholesterol/HDL Ratio is <4.5 optimal, <5.0 acceptable. Optimal ranges may differ based on individual health goals and expert recommendations.
Which blood test providers include Total Cholesterol/HDL Ratio?
7 out of 22 blood testing providers include Total Cholesterol/HDL Ratio in their panels. This biomarker is widely available across major providers.
What category does Total Cholesterol/HDL Ratio fall under?
Total Cholesterol/HDL Ratio is categorized under Lipid Panel / Cardiovascular Health. This category includes biomarkers that help assess related aspects of health and wellness.
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Medical Disclaimer
This information is for educational purposes only and is not medical advice. Always consult with a qualified healthcare provider about your specific health needs.
Last reviewed:2026-04-12