Urine Leukocyte Esterase
Leukocyte esterase is an enzyme released by white blood cells in urine, and a positive dipstick indicates the presence of pyuria. Together with urine nitrite it is used to screen for urinary tract infection, though positive results can also occur with kidney inflammation, interstitial nephritis, and nearby pelvic or vaginal infections. A urine culture is used to confirm and identify the organism.
4 providers include this
Urinalysis
Negative
What is Urine Leukocyte Esterase?
Leukocyte esterase is an enzyme released by white blood cells in urine, and a positive dipstick indicates the presence of pyuria. Together with urine nitrite it is used to screen for urinary tract infection, though positive results can also occur with kidney inflammation, interstitial nephritis, and nearby pelvic or vaginal infections. A urine culture is used to confirm and identify the organism.
Why It Matters
An enzyme released by white blood cells. A positive test indicates WBCs in urine, suggesting urinary tract infection or inflammation. Often combined with nitrite testing to screen for bacterial UTI.
Which Providers Test Urine Leukocyte Esterase?
Full Provider Comparison
| Provider | Includes | Annual Cost | Biomarkers |
|---|---|---|---|
 Superpower | — | $199 | 100+ (150 with ratios) |
 WHOOP Advanced Labs | — | $349 | 65 |
 Labcorp OnDemand | — | $398 | 40+ |
| — | $486 | 40+ | |
| — | $449 | 288 | |
| ✓ | $349 | 100+ | |
| — | $829 | 54 | |
 Function Health | — | $365 | 160+ |
| — | $250 | 65 | |
| — | $495 | 80+ | |
| — | $895 | 100+ | |
| — | $1950 | 130+ | |
| ✓ | $375 | 95+ | |
| — | $Varies | 75+ | |
| ✓ | $190 | 100+ | |
| — | $99 | 50 | |
| — | $124 | 60 | |
| — | $349 | 130+ | |
| — | $349 | 80+ | |
| — | $375 | 85 | |
| — | $700 | 128 | |
| ✓ | $99 | 100+ |
Frequently Asked Questions
What is Urine Leukocyte Esterase?
Leukocyte esterase is an enzyme released by white blood cells in urine, and a positive dipstick indicates the presence of pyuria. Together with urine nitrite it is used to screen for urinary tract infection, though positive results can also occur with kidney inflammation, interstitial nephritis, and nearby pelvic or vaginal infections. A urine culture is used to confirm and identify the organism.
What is the optimal range for Urine Leukocyte Esterase?
The standard reference range for Urine Leukocyte Esterase is Negative. Optimal ranges may differ based on individual health goals and expert recommendations.
Which blood test providers include Urine Leukocyte Esterase?
4 out of 22 blood testing providers include Urine Leukocyte Esterase in their panels. This biomarker has limited availability.
What category does Urine Leukocyte Esterase fall under?
Urine Leukocyte Esterase is categorized under Urinalysis. This category includes biomarkers that help assess related aspects of health and wellness.
Medical Disclaimer
This information is for educational purposes only and is not medical advice. Always consult with a qualified healthcare provider about your specific health needs.
Last reviewed:2026-04-12