ANA Screen (Antinuclear Antibodies)
The ANA screen detects antibodies directed against components of the cell nucleus and is a first-line test for systemic autoimmune disease. It is typically positive in lupus, scleroderma, Sjogren syndrome, and mixed connective tissue disease, but low-titer positives also occur in healthy older adults. A positive result usually prompts specific antibody testing to identify the underlying condition.
5 providers include this
Autoimmune Markers
Negative (titer <1:40)
What is ANA Screen (Antinuclear Antibodies)?
The ANA screen detects antibodies directed against components of the cell nucleus and is a first-line test for systemic autoimmune disease. It is typically positive in lupus, scleroderma, Sjogren syndrome, and mixed connective tissue disease, but low-titer positives also occur in healthy older adults. A positive result usually prompts specific antibody testing to identify the underlying condition.
Why It Matters
Screens for systemic autoimmune diseases like lupus and scleroderma. Positive result requires further testing to identify specific antibodies.
Which Providers Test ANA Screen (Antinuclear Antibodies)?
Full Provider Comparison
| Provider | Includes | Annual Cost | Biomarkers |
|---|---|---|---|
 Superpower | ✓ | $199 | 100+ (150 with ratios) |
 WHOOP Advanced Labs | — | $349 | 65 |
 Labcorp OnDemand | — | $398 | 40+ |
| — | $486 | 40+ | |
| — | $449 | 288 | |
| — | $349 | 100+ | |
| — | $829 | 54 | |
 Function Health | ✓ | $365 | 160+ |
| — | $250 | 65 | |
| — | $495 | 80+ | |
| — | $895 | 100+ | |
| — | $1950 | 130+ | |
| ✓ | $375 | 95+ | |
| — | $Varies | 75+ | |
| — | $190 | 100+ | |
| — | $99 | 50 | |
| — | $124 | 60 | |
| — | $349 | 130+ | |
| ✓ | $349 | 80+ | |
| — | $375 | 85 | |
| — | $700 | 128 | |
| ✓ | $99 | 100+ |
Frequently Asked Questions
What is ANA Screen (Antinuclear Antibodies)?
The ANA screen detects antibodies directed against components of the cell nucleus and is a first-line test for systemic autoimmune disease. It is typically positive in lupus, scleroderma, Sjogren syndrome, and mixed connective tissue disease, but low-titer positives also occur in healthy older adults. A positive result usually prompts specific antibody testing to identify the underlying condition.
What is the optimal range for ANA Screen (Antinuclear Antibodies)?
The standard reference range for ANA Screen (Antinuclear Antibodies) is Negative (titer <1:40). Optimal ranges may differ based on individual health goals and expert recommendations.
Which blood test providers include ANA Screen (Antinuclear Antibodies)?
5 out of 22 blood testing providers include ANA Screen (Antinuclear Antibodies) in their panels. This biomarker has limited availability.
What category does ANA Screen (Antinuclear Antibodies) fall under?
ANA Screen (Antinuclear Antibodies) is categorized under Autoimmune Markers. This category includes biomarkers that help assess related aspects of health and wellness.
Medical Disclaimer
This information is for educational purposes only and is not medical advice. Always consult with a qualified healthcare provider about your specific health needs.
Last reviewed:2026-04-12