De Ritis Ratio (AST/ALT)
The De Ritis ratio divides AST by ALT and helps clarify the cause of elevated liver enzymes. Ratios above 2 suggest alcoholic liver disease, while ratios below 1 are more typical of viral hepatitis or nonalcoholic fatty liver disease. Very high ratios can also accompany cirrhosis, ischemic hepatitis, and muscle injury since AST is also found in muscle.
3 providers include this
Liver Function
0.8-1.0 normal
What is De Ritis Ratio (AST/ALT)?
The De Ritis ratio divides AST by ALT and helps clarify the cause of elevated liver enzymes. Ratios above 2 suggest alcoholic liver disease, while ratios below 1 are more typical of viral hepatitis or nonalcoholic fatty liver disease. Very high ratios can also accompany cirrhosis, ischemic hepatitis, and muscle injury since AST is also found in muscle.
Why It Matters
Compares two liver enzymes to distinguish between liver disease types. Ratio above 2 often suggests alcoholic liver disease;below 1 suggests viral hepatitis. Helps guide diagnosis and treatment decisions.
Which Providers Test De Ritis Ratio (AST/ALT)?
Full Provider Comparison
| Provider | Includes | Annual Cost | Biomarkers |
|---|---|---|---|
 Superpower | ✓ | $199 | 100+ (150 with ratios) |
 WHOOP Advanced Labs | — | $349 | 65 |
 Labcorp OnDemand | — | $398 | 40+ |
| — | $486 | 40+ | |
| — | $449 | 288 | |
| — | $349 | 100+ | |
| — | $829 | 54 | |
 Function Health | — | $365 | 160+ |
| — | $250 | 65 | |
| — | $495 | 80+ | |
| — | $895 | 100+ | |
| — | $1950 | 130+ | |
| — | $375 | 95+ | |
| — | $Varies | 75+ | |
| ✓ | $190 | 100+ | |
| — | $99 | 50 | |
| — | $124 | 60 | |
| ✓ | $349 | 130+ | |
| — | $349 | 80+ | |
| — | $375 | 85 | |
| — | $700 | 128 | |
| — | $99 | 100+ |
Frequently Asked Questions
What is De Ritis Ratio (AST/ALT)?
The De Ritis ratio divides AST by ALT and helps clarify the cause of elevated liver enzymes. Ratios above 2 suggest alcoholic liver disease, while ratios below 1 are more typical of viral hepatitis or nonalcoholic fatty liver disease. Very high ratios can also accompany cirrhosis, ischemic hepatitis, and muscle injury since AST is also found in muscle.
What is the optimal range for De Ritis Ratio (AST/ALT)?
The standard reference range for De Ritis Ratio (AST/ALT) is 0.8-1.0 normal. Optimal ranges may differ based on individual health goals and expert recommendations.
Which blood test providers include De Ritis Ratio (AST/ALT)?
3 out of 22 blood testing providers include De Ritis Ratio (AST/ALT) in their panels. This biomarker has limited availability.
What category does De Ritis Ratio (AST/ALT) fall under?
De Ritis Ratio (AST/ALT) is categorized under Liver Function. This category includes biomarkers that help assess related aspects of health and wellness.
Want to improve this marker? YouBoost rates health interventions by evidence strength.
Medical Disclaimer
This information is for educational purposes only and is not medical advice. Always consult with a qualified healthcare provider about your specific health needs.
Last reviewed:2026-04-12