Lipase
Lipase is a digestive enzyme produced mainly by pancreatic acinar cells that hydrolyzes dietary triglycerides. Serum levels rise sharply in acute pancreatitis and remain elevated longer than amylase, making lipase the preferred diagnostic test. Elevations can also occur with pancreatic duct obstruction, bowel ischemia, or kidney failure that reduces clearance.
5 providers include this
Liver Function
10-140 U/L
What is Lipase?
Lipase is a digestive enzyme produced mainly by pancreatic acinar cells that hydrolyzes dietary triglycerides. Serum levels rise sharply in acute pancreatitis and remain elevated longer than amylase, making lipase the preferred diagnostic test. Elevations can also occur with pancreatic duct obstruction, bowel ischemia, or kidney failure that reduces clearance.
Why It Matters
Primary marker for pancreatitis. Elevated in pancreatic inflammation or damage. More specific than amylase for pancreatic disease. Can indicate gallbladder issues.
Which Providers Test Lipase?
Full Provider Comparison
| Provider | Includes | Annual Cost | Biomarkers |
|---|---|---|---|
 Superpower | — | $199 | 100+ (150 with ratios) |
 WHOOP Advanced Labs | — | $349 | 65 |
 Labcorp OnDemand | — | $398 | 40+ |
| — | $486 | 40+ | |
| — | $449 | 288 | |
| ✓ | $349 | 100+ | |
| — | $829 | 54 | |
 Function Health | ✓ | $365 | 160+ |
| — | $250 | 65 | |
| — | $495 | 80+ | |
| — | $895 | 100+ | |
| ✓ | $1950 | 130+ | |
| ✓ | $375 | 95+ | |
| — | $Varies | 75+ | |
| — | $190 | 100+ | |
| — | $99 | 50 | |
| — | $124 | 60 | |
| — | $349 | 130+ | |
| — | $349 | 80+ | |
| — | $375 | 85 | |
| — | $700 | 128 | |
| ✓ | $99 | 100+ |
Frequently Asked Questions
What is Lipase?
Lipase is a digestive enzyme produced mainly by pancreatic acinar cells that hydrolyzes dietary triglycerides. Serum levels rise sharply in acute pancreatitis and remain elevated longer than amylase, making lipase the preferred diagnostic test. Elevations can also occur with pancreatic duct obstruction, bowel ischemia, or kidney failure that reduces clearance.
What is the optimal range for Lipase?
The standard reference range for Lipase is 10-140 U/L. Optimal ranges may differ based on individual health goals and expert recommendations.
Which blood test providers include Lipase?
5 out of 22 blood testing providers include Lipase in their panels. This biomarker has limited availability.
What category does Lipase fall under?
Lipase is categorized under Liver Function. This category includes biomarkers that help assess related aspects of health and wellness.
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Medical Disclaimer
This information is for educational purposes only and is not medical advice. Always consult with a qualified healthcare provider about your specific health needs.
Last reviewed:2026-04-12