Transferrin Saturation
Transferrin saturation is the percentage of iron-binding sites on transferrin that are occupied and is calculated from serum iron divided by TIBC. Low values indicate iron deficiency, while values above about 45 percent suggest iron overload conditions such as hereditary hemochromatosis. It is interpreted together with ferritin for a complete picture of iron status.
14 of 22 providers
Additional Specialized Tests
Men:20-50%, Women:15-50%
What is Transferrin Saturation?
Transferrin saturation is the percentage of iron-binding sites on transferrin that are occupied and is calculated from serum iron divided by TIBC. Low values indicate iron deficiency, while values above about 45 percent suggest iron overload conditions such as hereditary hemochromatosis. It is interpreted together with ferritin for a complete picture of iron status.
Why It Matters
Reflects how much iron is being transported. Low in iron deficiency;high in iron overload (hemochromatosis). Critical for diagnosing iron disorders.
Which Providers Test Transferrin Saturation?
Full Provider Comparison
| Provider | Includes | Annual Cost | Biomarkers |
|---|---|---|---|
 Superpower | ✓ | $199 | 100+ (150 with ratios) |
 WHOOP Advanced Labs | ✓ | $349 | 65 |
 Labcorp OnDemand | — | $398 | 40+ |
| — | $486 | 40+ | |
| — | $449 | 288 | |
| ✓ | $349 | 100+ | |
| ✓ | $829 | 54 | |
 Function Health | ✓ | $365 | 160+ |
| — | $250 | 65 | |
| — | $495 | 80+ | |
| — | $895 | 100+ | |
| ✓ | $1950 | 130+ | |
| ✓ | $375 | 95+ | |
| — | $Varies | 75+ | |
| ✓ | $190 | 100+ | |
| — | $99 | 50 | |
| ✓ | $124 | 60 | |
| ✓ | $349 | 130+ | |
| ✓ | $349 | 80+ | |
| ✓ | $375 | 85 | |
| ✓ | $700 | 128 | |
| ✓ | $99 | 100+ |
Frequently Asked Questions
What is Transferrin Saturation?
Transferrin saturation is the percentage of iron-binding sites on transferrin that are occupied and is calculated from serum iron divided by TIBC. Low values indicate iron deficiency, while values above about 45 percent suggest iron overload conditions such as hereditary hemochromatosis. It is interpreted together with ferritin for a complete picture of iron status.
What is the optimal range for Transferrin Saturation?
The standard reference range for Transferrin Saturation is Men:20-50%, Women:15-50%. Optimal ranges may differ based on individual health goals and expert recommendations.
Which blood test providers include Transferrin Saturation?
14 out of 22 blood testing providers include Transferrin Saturation in their panels. This biomarker is widely available across major providers.
What category does Transferrin Saturation fall under?
Transferrin Saturation is categorized under Additional Specialized Tests. This category includes biomarkers that help assess related aspects of health and wellness.
Medical Disclaimer
This information is for educational purposes only and is not medical advice. Always consult with a qualified healthcare provider about your specific health needs.
Last reviewed:2026-04-12