Systemic Inflammation Index (SII)

Combined inflammatory marker

1/22Providers
Additional SpecCategory
<500 optimal, >1000 Reference
Limited Availability

1 providers include this

Category

Additional Specialized Tests

Reference Range

<500 optimal, >1000 elevated

What is Systemic Inflammation Index (SII)?

Combined inflammatory marker

Why It Matters

Calculated from platelet, neutrophil, and lymphocyte counts. Elevated SII predicts cardiovascular events, cancer prognosis, and all-cause mortality. More comprehensive than single inflammatory markers.

Reference Range: <500 optimal, >1000 elevated

Which Providers Test Systemic Inflammation Index (SII)?

Superpower
Included in panel

Full Provider Comparison

ProviderIncludesAnnual CostBiomarkers
SuperpowerSuperpower✓$199100+ (150 with ratios)
WHOOP Advanced LabsWHOOP Advanced Labs—$34965
Labcorp OnDemandLabcorp OnDemand—$39830+
Life ExtensionLife Extension—$48640+
EverlywellEverlywell—$444288
Mito HealthMito Health—$349100+
InsideTrackerInsideTracker—$76154
Function HealthFunction Health—$365160+
Marek Health BaseMarek Health Base—$25065
Marek Health ComprehensiveMarek Health Comprehensive—$49570+
Marek Health CompleteMarek Health Complete—$895100+
Marek Health ExecutiveMarek Health Executive—$1950150+
BlueprintBlueprint—$37580+
Quest HealthQuest Health—$Varies75+
Empirical HealthEmpirical Health—$190100+
Oura Health PanelsOura Health Panels—$9950
SiPhox HealthSiPhox Health—$12460
Hims Labs BaseHims Labs Base—$19950
Hims Labs AdvancedHims Labs Advanced—$499120+
HealthspanHealthspan—$418870-80+
Vitality Blueprint StandardVitality Blueprint Standard—$37585
Vitality Blueprint EliteVitality Blueprint Elite—$700128

Related Biomarkers

Other biomarkers in the Additional Specialized Tests category:

Neutrophil/Lymphocyte Ratio Platelet/Lymphocyte Ratio Monocyte/HDL Ratio LDL-P (LDL Particle Number) LDL Particle Size Analysis HDL Subfractions (Large/Small) Transferrin Saturation GGT/HDL Ratio

Frequently Asked Questions

What is Systemic Inflammation Index (SII)?

Combined inflammatory marker

What is the optimal range for Systemic Inflammation Index (SII)?

The standard reference range for Systemic Inflammation Index (SII) is <500 optimal, >1000 elevated. Optimal ranges may differ based on individual health goals and expert recommendations.

Which blood test providers include Systemic Inflammation Index (SII)?

1 out of 22 blood testing providers include Systemic Inflammation Index (SII) in their panels. This biomarker has limited availability.

What category does Systemic Inflammation Index (SII) fall under?

Systemic Inflammation Index (SII) is categorized under Additional Specialized Tests. This category includes biomarkers that help assess related aspects of health and wellness.

Medical Disclaimer

This information is for educational purposes only and is not medical advice. Always consult with a qualified healthcare provider about your specific health needs.

Last reviewed:2026-02-20