Blueprint vs SiPhox Health
Complete Head-to-Head Comparison
Compare costs, biomarker coverage, and value to find the best blood testing service for your needs
Blueprint
Quick Comparison Summary
Best Value
Blueprint
27.4 biomarkers per $100
Most Comprehensive
Blueprint
100+ biomarkers tested
Most Tests Per Year
SiPhox Health
4 tests/year
Cost & Value Comparison
Blueprint
Annual Cost$365
Tests per Year2
Total Biomarkers100+
Cost per Test$182
SiPhox Health
Annual Cost$496
Tests per Year4
Total Biomarkers59
Cost per Test$124
Service Details
| Feature | Blueprint | SiPhox Health |
|---|---|---|
| Lab Locations | Labcorp (3500+) | At-home |
| Key Features | Bryan Johnson protocol, Don't Die app results, personalized longevity protocols | Needle-free EasyDraw device, AI longevity expert (Sai), wearable integrations (Oura/Fitbit/Apple Watch), supplement recommendations, third-party lab uploads |
| Notes | Restructured to a $365/year Biomarkers membership ($1/day, billed annually):two blood panels plus urine per year - a baseline of up to 140 biomarkers and a 6-month follow-up of up to 86, marketed as 100+ biomarkers and 160+ measurements per year. Labcorp partnership, 3,500+ US draw locations. One-time panels still sold separately:Basic $375 (67 biomarkers), Advanced $575 (108 biomarkers). Speed of Aging epigenetic test $325 and Microplastics test $135 are separate and not bundled. HSA/FSA eligible. | Membership billed per test cycle at $124 (monthly, quarterly or every 6 months - same price per cycle). At the quarterly cadence shown here that is 4 x $124=$496/yr plus shipping. Four core panels included and switchable:Longevity Essentials (25 biomarkers), Thyroid Focus, Hormone Focus, Heart &Metabolic. Ultimate 360 is a paid upgrade at +$125/cycle (59 biomarkers);GLP Monitoring Panel +$75/cycle. At-home needle-free EasyDraw collection. Our 20% affiliate code applies to the first billing cycle only, membership only, excluding shipping and upgrades. HSA/FSA eligible. |
Biomarker Coverage Comparison
44
Tests in Common
75
Only in Blueprint
4
Only in SiPhox Health
Tests Only in Blueprint
- MCH (Mean Corpuscular Hemoglobin)(Complete Blood Count (CBC))
- MCHC (Mean Corpuscular Hemoglobin Concentration)(Complete Blood Count (CBC))
- ABO Blood Type(Complete Blood Count (CBC))
- Hematocrit(Complete Blood Count (CBC))
- Red Blood Cell Count (RBC)(Complete Blood Count (CBC))
- White Blood Cell Count (WBC)(Complete Blood Count (CBC))
- Platelet Count(Complete Blood Count (CBC))
- MCV, MCH, MCHC(Complete Blood Count (CBC))
- RDW (Red Cell Distribution Width)(Complete Blood Count (CBC))
- Fasting Glucose(Metabolic Health / Glucose)
- Insulin(Metabolic Health / Glucose)
- Uric Acid(Metabolic Health / Glucose)
- GGT (Gamma-Glutamyl Transferase)(Liver Function)
- Sodium(Electrolytes &Minerals)
- Potassium(Electrolytes &Minerals)
- Chloride(Electrolytes &Minerals)
- Carbon Dioxide (CO2)(Electrolytes &Minerals)
- Magnesium(Electrolytes &Minerals)
- Total T4(Thyroid Function)
- TIBC (Total Iron Binding Capacity)(Vitamins &Nutrients)
- Omega-3 Index / Fatty Acids(Advanced / Specialty Markers)
- Arachidonic Acid / EPA Ratio(Advanced / Specialty Markers)
- Heavy Metals - Lead(Advanced / Specialty Markers)
- Heavy Metals - Mercury(Advanced / Specialty Markers)
- IGF-1 (Insulin-like Growth Factor)(Advanced / Specialty Markers)
- ANA Screen (Antinuclear Antibodies)(Autoimmune Markers)
- ANA Titer(Autoimmune Markers)
- ANA Pattern(Autoimmune Markers)
- Rheumatoid Factor (RF)(Autoimmune Markers)
- PSA Free (Prostate Cancer)(Cancer Screening Markers)
- Mean Platelet Volume (MPV)(Complete Blood Count (CBC))
- Zinc(Electrolytes &Minerals)
- Lipase(Liver Function)
- Leptin(Advanced / Specialty Markers)
- Omega-6 Total(Advanced / Specialty Markers)
- Linoleic Acid(Advanced / Specialty Markers)
- Arachidonic Acid(Advanced / Specialty Markers)
- Neutrophils(Complete Blood Count (CBC))
- Lymphocytes(Complete Blood Count (CBC))
- Monocytes(Complete Blood Count (CBC))
- Eosinophils(Complete Blood Count (CBC))
- Basophils(Complete Blood Count (CBC))
- Non-HDL Cholesterol(Lipid Panel / Cardiovascular Health)
- Urine Appearance(Urinalysis)
- Urine Albumin(Urinalysis)
- Urine Color(Urinalysis)
- Urine pH(Urinalysis)
- Urine Specific Gravity(Urinalysis)
- Urine Protein(Urinalysis)
- Urine Glucose(Urinalysis)
- Urine Ketones(Urinalysis)
- Urine Bilirubin(Urinalysis)
- Urine Blood (Occult)(Urinalysis)
- Urine Nitrite(Urinalysis)
- Urine Leukocyte Esterase(Urinalysis)
- Urine WBC(Urinalysis)
- Urine RBC(Urinalysis)
- Urine Bacteria(Urinalysis)
- Squamous Epithelial Cells (Urine)(Urinalysis)
- Transitional Epithelial Cells (Urine)(Urinalysis)
- Renal Epithelial Cells (Urine)(Urinalysis)
- Hyaline Casts (Urine)(Urinalysis)
- Granular Casts (Urine)(Urinalysis)
- Urine Crystals(Urinalysis)
- Calcium Oxalate Crystals (Urine)(Urinalysis)
- Uric Acid Crystals (Urine)(Urinalysis)
- Triple Phosphate Crystals (Urine)(Urinalysis)
- Yeast (Urine)(Urinalysis)
- Reducing Substances (Urine)(Urinalysis)
- LDL Small(Lipid Panel / Cardiovascular)
- LDL Medium(Lipid Panel / Cardiovascular)
- LDL Pattern(Lipid Panel / Cardiovascular)
- LDL Peak Size(Lipid Panel / Cardiovascular)
- Omega-6/Omega-3 Ratio(Lipid Panel / Cardiovascular)
- Amylase(Pancreas &Digestive)
Tests Only in SiPhox Health
- TPO Antibodies (Thyroid Peroxidase)(Thyroid Function)
- Thyroglobulin Antibodies(Thyroid Function)
- AMH (Anti-Mullerian Hormone)(Sex Hormones (Female))
- Free Androgen Index (FAI)(Additional Specialized Tests)
Complete Biomarker Comparison by Category
Filter by Category
Ready to Choose?
Based on this comparison, make an informed decision about your blood testing provider
Frequently Asked Questions
Which provider is better:Blueprint or SiPhox Health?
Blueprint offers better value with 27.4 biomarkers per $100 spent, making it more cost-effective for comprehensive testing.
However, the best choice depends on your specific health goals, budget, and which biomarkers are most important for your situation.
How much do Blueprint and SiPhox Health cost per year?
Blueprint costs $365 per year for 2,
while SiPhox Health costs $496 per year for 4.
The cost per test is $182
for Blueprint and $124
for SiPhox Health.
What biomarkers does Blueprint test that SiPhox Health doesn't?
Blueprint includes 75 unique biomarkers not found in SiPhox Health's panel.
These include MCH (Mean Corpuscular Hemoglobin), MCHC (Mean Corpuscular Hemoglobin Concentration), ABO Blood Type, and others.
Can I use insurance with Blueprint or SiPhox Health?
Both Blueprint and SiPhox Health are direct-to-consumer services that typically don't accept insurance.
However, you may be able to submit receipts to your insurance for reimbursement if you have out-of-network benefits,
or use HSA/FSA funds for payment. Check with your insurance provider and the testing companies for specific policies.
How often should I get blood work done?
Most health optimization experts recommend testing 2-4 times per year to establish baselines and track trends.
Blueprint includes 2 in their annual membership,
while SiPhox Health includes 4.
More frequent testing allows you to track the effectiveness of interventions and catch changes early.
Where can I get blood drawn for these tests?
Blueprint uses Labcorp (3500+),
while SiPhox Health uses At-home.
Both typically have thousands of collection centers nationwide. You'll schedule your blood draw through their platform after ordering.
Frequently Asked Questions
Which is cheaper, Blueprint or SiPhox Health?
Blueprint is cheaper at $365/year compared to SiPhox Health at $496/year.
Which tests more biomarkers, Blueprint or SiPhox Health?
Blueprint tests 100+ biomarkers while SiPhox Health tests 59 biomarkers.
What is Blueprint best for?
Blueprint offers 100+ biomarkers for $365/year with 2 test(s) per year. Key features include:Bryan Johnson protocol, Don't Die app results, personalized longevity protocols
What is SiPhox Health best for?
SiPhox Health offers 59 biomarkers for $496/year with 4 test(s) per year. Key features include:Needle-free EasyDraw device, AI longevity expert (Sai), wearable integrations (Oura/Fitbit/Apple Watch), supplement recommendations, third-party lab uploads
Which offers better value, Blueprint or SiPhox Health?
Blueprint offers better value with approximately 27.4 biomarkers per $100 spent, compared to SiPhox Health's 11.9 biomarkers per $100.