Blueprint vs SiPhox Health
Complete Head-to-Head Comparison
Compare costs, biomarker coverage, and value to find the best blood testing service for your needs
Blueprint
Quick Comparison Summary
Best Value
SiPhox Health
48.4 biomarkers per $100
Most Comprehensive
Blueprint
95+ biomarkers tested
Most Tests Per Year
SiPhox Health
4 tests/year
Cost & Value Comparison
Blueprint
Annual Cost$375
Tests per Year1
Total Biomarkers95+
Cost per Test$375
SiPhox Health
Annual Cost$124
Tests per Year4
Total Biomarkers60
Cost per Test$31
Service Details
| Feature | Blueprint | SiPhox Health |
|---|---|---|
| Lab Locations | Labcorp (3500+) | At-home |
| Key Features | Bryan Johnson protocol, Don't Die app results, personalized longevity protocols | Needle-free EasyDraw device, AI longevity expert (Sai), wearable integrations (Oura/Fitbit/Apple Watch), supplement recommendations, third-party lab uploads |
| Notes | Basic Panel $375 (95+ biomarkers). Advanced Panel $575 (100+ biomarkers, adds thyroid, omega fatty acids, autoimmune markers). Microplastics test also available. Speed of Aging epigenetic test separate. Results in 4-6 weeks. Not available in NJ, NY, RI, HI. | $124/test. Ultimate 360 panel has 60 biomarkers. Results in 7-10 days. HSA/FSA eligible. Use our link for 20% off |
Biomarker Coverage Comparison
44
Tests in Common
75
Only in Blueprint
4
Only in SiPhox Health
Tests Only in Blueprint
- MCH (Mean Corpuscular Hemoglobin)(Complete Blood Count (CBC))
- MCHC (Mean Corpuscular Hemoglobin Concentration)(Complete Blood Count (CBC))
- ABO Blood Type(Complete Blood Count (CBC))
- Hematocrit(Complete Blood Count (CBC))
- Red Blood Cell Count (RBC)(Complete Blood Count (CBC))
- White Blood Cell Count (WBC)(Complete Blood Count (CBC))
- Platelet Count(Complete Blood Count (CBC))
- MCV, MCH, MCHC(Complete Blood Count (CBC))
- RDW (Red Cell Distribution Width)(Complete Blood Count (CBC))
- Fasting Glucose(Metabolic Health / Glucose)
- Insulin(Metabolic Health / Glucose)
- Uric Acid(Metabolic Health / Glucose)
- GGT (Gamma-Glutamyl Transferase)(Liver Function)
- Sodium(Electrolytes &Minerals)
- Potassium(Electrolytes &Minerals)
- Chloride(Electrolytes &Minerals)
- Carbon Dioxide (CO2)(Electrolytes &Minerals)
- Magnesium(Electrolytes &Minerals)
- Total T4(Thyroid Function)
- TIBC (Total Iron Binding Capacity)(Vitamins &Nutrients)
- Omega-3 Index / Fatty Acids(Advanced / Specialty Markers)
- Arachidonic Acid / EPA Ratio(Advanced / Specialty Markers)
- Heavy Metals - Lead(Advanced / Specialty Markers)
- Heavy Metals - Mercury(Advanced / Specialty Markers)
- IGF-1 (Insulin-like Growth Factor)(Advanced / Specialty Markers)
- ANA Screen (Antinuclear Antibodies)(Autoimmune Markers)
- ANA Titer(Autoimmune Markers)
- ANA Pattern(Autoimmune Markers)
- Rheumatoid Factor (RF)(Autoimmune Markers)
- PSA Free (Prostate Cancer)(Cancer Screening Markers)
- Mean Platelet Volume (MPV)(Complete Blood Count (CBC))
- Zinc(Electrolytes &Minerals)
- Lipase(Liver Function)
- Leptin(Advanced / Specialty Markers)
- Omega-6 Total(Advanced / Specialty Markers)
- Linoleic Acid(Advanced / Specialty Markers)
- Arachidonic Acid(Advanced / Specialty Markers)
- Neutrophils(Complete Blood Count (CBC))
- Lymphocytes(Complete Blood Count (CBC))
- Monocytes(Complete Blood Count (CBC))
- Eosinophils(Complete Blood Count (CBC))
- Basophils(Complete Blood Count (CBC))
- Non-HDL Cholesterol(Lipid Panel / Cardiovascular Health)
- Urine Appearance(Urinalysis)
- Urine Albumin(Urinalysis)
- Urine Color(Urinalysis)
- Urine pH(Urinalysis)
- Urine Specific Gravity(Urinalysis)
- Urine Protein(Urinalysis)
- Urine Glucose(Urinalysis)
- Urine Ketones(Urinalysis)
- Urine Bilirubin(Urinalysis)
- Urine Blood (Occult)(Urinalysis)
- Urine Nitrite(Urinalysis)
- Urine Leukocyte Esterase(Urinalysis)
- Urine WBC(Urinalysis)
- Urine RBC(Urinalysis)
- Urine Bacteria(Urinalysis)
- Squamous Epithelial Cells (Urine)(Urinalysis)
- Transitional Epithelial Cells (Urine)(Urinalysis)
- Renal Epithelial Cells (Urine)(Urinalysis)
- Hyaline Casts (Urine)(Urinalysis)
- Granular Casts (Urine)(Urinalysis)
- Urine Crystals(Urinalysis)
- Calcium Oxalate Crystals (Urine)(Urinalysis)
- Uric Acid Crystals (Urine)(Urinalysis)
- Triple Phosphate Crystals (Urine)(Urinalysis)
- Yeast (Urine)(Urinalysis)
- Reducing Substances (Urine)(Urinalysis)
- LDL Small(Lipid Panel / Cardiovascular)
- LDL Medium(Lipid Panel / Cardiovascular)
- LDL Pattern(Lipid Panel / Cardiovascular)
- LDL Peak Size(Lipid Panel / Cardiovascular)
- Omega-6/Omega-3 Ratio(Lipid Panel / Cardiovascular)
- Amylase(Pancreas &Digestive)
Tests Only in SiPhox Health
- TPO Antibodies (Thyroid Peroxidase)(Thyroid Function)
- Thyroglobulin Antibodies(Thyroid Function)
- AMH (Anti-Mullerian Hormone)(Sex Hormones (Female))
- Free Androgen Index (FAI)(Additional Specialized Tests)
Complete Biomarker Comparison by Category
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Ready to Choose?
Based on this comparison, make an informed decision about your blood testing provider
Frequently Asked Questions
Which provider is better:Blueprint or SiPhox Health?
SiPhox Health provides better value with 48.4 biomarkers per $100 spent, offering more comprehensive coverage for your investment.
However, the best choice depends on your specific health goals, budget, and which biomarkers are most important for your situation.
How much do Blueprint and SiPhox Health cost per year?
Blueprint costs $375 per year for 1,
while SiPhox Health costs $124 per year for 4.
The cost per test is $375
for Blueprint and $31
for SiPhox Health.
What biomarkers does Blueprint test that SiPhox Health doesn't?
Blueprint includes 75 unique biomarkers not found in SiPhox Health's panel.
These include MCH (Mean Corpuscular Hemoglobin), MCHC (Mean Corpuscular Hemoglobin Concentration), ABO Blood Type, and others.
Can I use insurance with Blueprint or SiPhox Health?
Both Blueprint and SiPhox Health are direct-to-consumer services that typically don't accept insurance.
However, you may be able to submit receipts to your insurance for reimbursement if you have out-of-network benefits,
or use HSA/FSA funds for payment. Check with your insurance provider and the testing companies for specific policies.
How often should I get blood work done?
Most health optimization experts recommend testing 2-4 times per year to establish baselines and track trends.
Blueprint includes 1 in their annual membership,
while SiPhox Health includes 4.
More frequent testing allows you to track the effectiveness of interventions and catch changes early.
Where can I get blood drawn for these tests?
Blueprint uses Labcorp (3500+),
while SiPhox Health uses At-home.
Both typically have thousands of collection centers nationwide. You'll schedule your blood draw through their platform after ordering.
Frequently Asked Questions
Which is cheaper, Blueprint or SiPhox Health?
SiPhox Health is cheaper at $124/year compared to Blueprint at $375/year.
Which tests more biomarkers, Blueprint or SiPhox Health?
Blueprint tests 95+ biomarkers while SiPhox Health tests 60 biomarkers.
What is Blueprint best for?
Blueprint offers 95+ biomarkers for $375/year with 1 test(s) per year. Key features include:Bryan Johnson protocol, Don't Die app results, personalized longevity protocols
What is SiPhox Health best for?
SiPhox Health offers 60 biomarkers for $124/year with 4 test(s) per year. Key features include:Needle-free EasyDraw device, AI longevity expert (Sai), wearable integrations (Oura/Fitbit/Apple Watch), supplement recommendations, third-party lab uploads
Which offers better value, Blueprint or SiPhox Health?
SiPhox Health offers better value with approximately 48.4 biomarkers per $100 spent, compared to Blueprint's 25.3 biomarkers per $100.