TPO Antibodies (Thyroid Peroxidase)
TPO antibodies target thyroid peroxidase, an enzyme in hormone synthesis, and are the most sensitive marker of autoimmune thyroid disease. They are present in most cases of Hashimoto's thyroiditis and in many with Graves disease. Elevated TPO antibodies also predict future progression to overt hypothyroidism in people with subclinical disease.
9 of 22 providers
Thyroid Function
<35 IU/mL, Negative:<9 IU/mL
What is TPO Antibodies (Thyroid Peroxidase)?
TPO antibodies target thyroid peroxidase, an enzyme in hormone synthesis, and are the most sensitive marker of autoimmune thyroid disease. They are present in most cases of Hashimoto's thyroiditis and in many with Graves disease. Elevated TPO antibodies also predict future progression to overt hypothyroidism in people with subclinical disease.
Why It Matters
Elevated in Hashimoto's thyroiditis and Graves'disease. Helps diagnose autoimmune thyroid disorders. Predicts progression to hypothyroidism.
Which Providers Test TPO Antibodies (Thyroid Peroxidase)?
Full Provider Comparison
| Provider | Includes | Annual Cost | Biomarkers |
|---|---|---|---|
 Superpower | ✓ | $199 | 100+ (150 with ratios) |
 WHOOP Advanced Labs | — | $349 | 65 |
 Labcorp OnDemand | — | $398 | 40+ |
| — | $486 | 40+ | |
| — | $449 | 288 | |
| ✓ | $349 | 100+ | |
| — | $829 | 54 | |
 Function Health | ✓ | $365 | 160+ |
| — | $250 | 65 | |
| ✓ | $495 | 80+ | |
| ✓ | $895 | 100+ | |
| ✓ | $1950 | 130+ | |
| — | $375 | 95+ | |
| — | $Varies | 75+ | |
| — | $190 | 100+ | |
| — | $99 | 50 | |
| ✓ | $124 | 60 | |
| ✓ | $349 | 130+ | |
| — | $349 | 80+ | |
| — | $375 | 85 | |
| — | $700 | 128 | |
| ✓ | $99 | 100+ |
Frequently Asked Questions
What is TPO Antibodies (Thyroid Peroxidase)?
TPO antibodies target thyroid peroxidase, an enzyme in hormone synthesis, and are the most sensitive marker of autoimmune thyroid disease. They are present in most cases of Hashimoto's thyroiditis and in many with Graves disease. Elevated TPO antibodies also predict future progression to overt hypothyroidism in people with subclinical disease.
What is the optimal range for TPO Antibodies (Thyroid Peroxidase)?
The standard reference range for TPO Antibodies (Thyroid Peroxidase) is <35 IU/mL, Negative:<9 IU/mL. Optimal ranges may differ based on individual health goals and expert recommendations.
Which blood test providers include TPO Antibodies (Thyroid Peroxidase)?
9 out of 22 blood testing providers include TPO Antibodies (Thyroid Peroxidase) in their panels. This biomarker is widely available across major providers.
What category does TPO Antibodies (Thyroid Peroxidase) fall under?
TPO Antibodies (Thyroid Peroxidase) is categorized under Thyroid Function. This category includes biomarkers that help assess related aspects of health and wellness.
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Medical Disclaimer
This information is for educational purposes only and is not medical advice. Always consult with a qualified healthcare provider about your specific health needs.
Last reviewed:2026-04-12