Blueprint vs Healthspan
Complete Head-to-Head Comparison
Compare costs, biomarker coverage, and value to find the best blood testing service for your needs
Quick Comparison Summary
Best Value
Blueprint
27.4 biomarkers per $100
Most Comprehensive
Blueprint
100+ biomarkers tested
Most Tests Per Year
Healthspan
2 tests/year
Cost & Value Comparison
Blueprint
Annual Cost$365
Tests per Year2
Total Biomarkers100+
Cost per Test$182
Healthspan
Annual Cost$1188
Tests per Year2
Total Biomarkers70+
Cost per Test$594
Service Details
| Feature | Blueprint | Healthspan |
|---|---|---|
| Lab Locations | Labcorp (3500+) | CLIA-certified labs |
| Key Features | Bryan Johnson protocol, Don't Die app results, personalized longevity protocols | Biological age calculation, rapamycin/acarbose/metformin protocols, GLP-1 protocols, longevity-focused panels |
| Notes | Restructured to a $365/year Biomarkers membership ($1/day, billed annually):two blood panels plus urine per year - a baseline of up to 140 biomarkers and a 6-month follow-up of up to 86, marketed as 100+ biomarkers and 160+ measurements per year. Labcorp partnership, 3,500+ US draw locations. One-time panels still sold separately:Basic $375 (67 biomarkers), Advanced $575 (108 biomarkers). Speed of Aging epigenetic test $325 and Microplastics test $135 are separate and not bundled. HSA/FSA eligible. | Model changed from a standalone $349 panel to a $99/month Longevity Optimization membership;the $1,188 shown is that rate annualized, not a figure Healthspan advertises. Core tier includes labs at baseline and 6 months (2/yr) tracking 70+ biomarkers across 9 biological systems;the Advanced tier runs labs quarterly but its price is not published. Includes BioAge+ biological age testing, 1:1 PhD-level coaching and clinician access. Treatment protocols priced separately ($25-$135/mo). Standalone panel pricing is no longer published publicly. Not to be confused with the unrelated myhealthspan.com. |
Biomarker Coverage Comparison
64
Tests in Common
55
Only in Blueprint
8
Only in Healthspan
Tests Only in Blueprint
- MCH (Mean Corpuscular Hemoglobin)(Complete Blood Count (CBC))
- MCHC (Mean Corpuscular Hemoglobin Concentration)(Complete Blood Count (CBC))
- ABO Blood Type(Complete Blood Count (CBC))
- Magnesium(Electrolytes &Minerals)
- Total T4(Thyroid Function)
- Vitamin B12(Vitamins &Nutrients)
- Folate(Vitamins &Nutrients)
- Omega-3 Index / Fatty Acids(Advanced / Specialty Markers)
- Arachidonic Acid / EPA Ratio(Advanced / Specialty Markers)
- Heavy Metals - Lead(Advanced / Specialty Markers)
- Heavy Metals - Mercury(Advanced / Specialty Markers)
- ANA Titer(Autoimmune Markers)
- ANA Pattern(Autoimmune Markers)
- Rheumatoid Factor (RF)(Autoimmune Markers)
- PSA Free (Prostate Cancer)(Cancer Screening Markers)
- Mean Platelet Volume (MPV)(Complete Blood Count (CBC))
- Zinc(Electrolytes &Minerals)
- Lipase(Liver Function)
- Leptin(Advanced / Specialty Markers)
- Omega-6 Total(Advanced / Specialty Markers)
- Linoleic Acid(Advanced / Specialty Markers)
- Arachidonic Acid(Advanced / Specialty Markers)
- Non-HDL Cholesterol(Lipid Panel / Cardiovascular Health)
- Urine Appearance(Urinalysis)
- Urine Albumin(Urinalysis)
- Urine Color(Urinalysis)
- Urine pH(Urinalysis)
- Urine Specific Gravity(Urinalysis)
- Urine Protein(Urinalysis)
- Urine Glucose(Urinalysis)
- Urine Ketones(Urinalysis)
- Urine Bilirubin(Urinalysis)
- Urine Blood (Occult)(Urinalysis)
- Urine Nitrite(Urinalysis)
- Urine Leukocyte Esterase(Urinalysis)
- Urine WBC(Urinalysis)
- Urine RBC(Urinalysis)
- Urine Bacteria(Urinalysis)
- Squamous Epithelial Cells (Urine)(Urinalysis)
- Transitional Epithelial Cells (Urine)(Urinalysis)
- Renal Epithelial Cells (Urine)(Urinalysis)
- Hyaline Casts (Urine)(Urinalysis)
- Granular Casts (Urine)(Urinalysis)
- Urine Crystals(Urinalysis)
- Calcium Oxalate Crystals (Urine)(Urinalysis)
- Uric Acid Crystals (Urine)(Urinalysis)
- Triple Phosphate Crystals (Urine)(Urinalysis)
- Yeast (Urine)(Urinalysis)
- Reducing Substances (Urine)(Urinalysis)
- LDL Small(Lipid Panel / Cardiovascular)
- LDL Medium(Lipid Panel / Cardiovascular)
- LDL Pattern(Lipid Panel / Cardiovascular)
- LDL Peak Size(Lipid Panel / Cardiovascular)
- Omega-6/Omega-3 Ratio(Lipid Panel / Cardiovascular)
- Amylase(Pancreas &Digestive)
Tests Only in Healthspan
- LDL Particle Number(Lipid Panel / Cardiovascular Health)
- LDL Particle Size(Lipid Panel / Cardiovascular Health)
- AMH (Anti-Mullerian Hormone)(Sex Hormones (Female))
- ESR (Erythrocyte Sedimentation Rate)(Inflammation &Immune Markers)
- Neutrophil/Lymphocyte Ratio(Additional Specialized Tests)
- LDL-P (LDL Particle Number)(Additional Specialized Tests)
- LDL Particle Size Analysis(Additional Specialized Tests)
- HDL Subfractions (Large/Small)(Additional Specialized Tests)
Complete Biomarker Comparison by Category
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Ready to Choose?
Based on this comparison, make an informed decision about your blood testing provider
Frequently Asked Questions
Which provider is better:Blueprint or Healthspan?
Blueprint offers better value with 27.4 biomarkers per $100 spent, making it more cost-effective for comprehensive testing.
However, the best choice depends on your specific health goals, budget, and which biomarkers are most important for your situation.
How much do Blueprint and Healthspan cost per year?
Blueprint costs $365 per year for 2,
while Healthspan costs $1188 per year for 2.
The cost per test is $182
for Blueprint and $594
for Healthspan.
What biomarkers does Blueprint test that Healthspan doesn't?
Blueprint includes 55 unique biomarkers not found in Healthspan's panel.
These include MCH (Mean Corpuscular Hemoglobin), MCHC (Mean Corpuscular Hemoglobin Concentration), ABO Blood Type, and others.
Can I use insurance with Blueprint or Healthspan?
Both Blueprint and Healthspan are direct-to-consumer services that typically don't accept insurance.
However, you may be able to submit receipts to your insurance for reimbursement if you have out-of-network benefits,
or use HSA/FSA funds for payment. Check with your insurance provider and the testing companies for specific policies.
How often should I get blood work done?
Most health optimization experts recommend testing 2-4 times per year to establish baselines and track trends.
Blueprint includes 2 in their annual membership,
while Healthspan includes 2.
More frequent testing allows you to track the effectiveness of interventions and catch changes early.
Where can I get blood drawn for these tests?
Blueprint uses Labcorp (3500+),
while Healthspan uses CLIA-certified labs.
Both typically have thousands of collection centers nationwide. You'll schedule your blood draw through their platform after ordering.
Frequently Asked Questions
Which is cheaper, Blueprint or Healthspan?
Healthspan is cheaper at $1188/year compared to Blueprint at $365/year.
Which tests more biomarkers, Blueprint or Healthspan?
Blueprint tests 100+ biomarkers while Healthspan tests 70+ biomarkers.
What is Blueprint best for?
Blueprint offers 100+ biomarkers for $365/year with 2 test(s) per year. Key features include:Bryan Johnson protocol, Don't Die app results, personalized longevity protocols
What is Healthspan best for?
Healthspan offers 70+ biomarkers for $1188/year with 2 test(s) per year. Key features include:Biological age calculation, rapamycin/acarbose/metformin protocols, GLP-1 protocols, longevity-focused panels
Which offers better value, Blueprint or Healthspan?
Blueprint offers better value with approximately 27.4 biomarkers per $100 spent, compared to Healthspan's 5.9 biomarkers per $100.