Empirical Health vs SiPhox Health
Complete Head-to-Head Comparison
Compare costs, biomarker coverage, and value to find the best blood testing service for your needs
Empirical Health
Quick Comparison Summary
Best Value
Empirical Health
52.6 biomarkers per $100
Most Comprehensive
Empirical Health
100+ biomarkers tested
Most Tests Per Year
SiPhox Health
4 tests/year
Cost & Value Comparison
Empirical Health
Annual Cost$190
Tests per Year1
Total Biomarkers100+
Cost per Test$190
SiPhox Health
Annual Cost$496
Tests per Year4
Total Biomarkers59
Cost per Test$124
Service Details
| Feature | Empirical Health | SiPhox Health |
|---|---|---|
| Lab Locations | 2200+ locations | At-home |
| Key Features | Personalized MD video visit included, doctor messaging, custom nutrition plan, exercise routines, mobile app | Needle-free EasyDraw device, AI longevity expert (Sai), wearable integrations (Oura/Fitbit/Apple Watch), supplement recommendations, third-party lab uploads |
| Notes | $190 per test with MD video visit included. Single lab visit. HSA/FSA eligible | Membership billed per test cycle at $124 (monthly, quarterly or every 6 months - same price per cycle). At the quarterly cadence shown here that is 4 x $124=$496/yr plus shipping. Four core panels included and switchable:Longevity Essentials (25 biomarkers), Thyroid Focus, Hormone Focus, Heart &Metabolic. Ultimate 360 is a paid upgrade at +$125/cycle (59 biomarkers);GLP Monitoring Panel +$75/cycle. At-home needle-free EasyDraw collection. Our 20% affiliate code applies to the first billing cycle only, membership only, excluding shipping and upgrades. HSA/FSA eligible. |
Biomarker Coverage Comparison
30
Tests in Common
55
Only in Empirical Health
18
Only in SiPhox Health
Tests Only in Empirical Health
- Hematocrit(Complete Blood Count (CBC))
- Red Blood Cell Count (RBC)(Complete Blood Count (CBC))
- White Blood Cell Count (WBC)(Complete Blood Count (CBC))
- Platelet Count(Complete Blood Count (CBC))
- MCV, MCH, MCHC(Complete Blood Count (CBC))
- RDW (Red Cell Distribution Width)(Complete Blood Count (CBC))
- Fasting Glucose(Metabolic Health / Glucose)
- Insulin(Metabolic Health / Glucose)
- Uric Acid(Metabolic Health / Glucose)
- Sodium(Electrolytes &Minerals)
- Potassium(Electrolytes &Minerals)
- Chloride(Electrolytes &Minerals)
- Carbon Dioxide (CO2)(Electrolytes &Minerals)
- Magnesium(Electrolytes &Minerals)
- TIBC (Total Iron Binding Capacity)(Vitamins &Nutrients)
- Mean Platelet Volume (MPV)(Complete Blood Count (CBC))
- Apolipoprotein A1 (ApoA1)(Lipid Panel / Cardiovascular Health)
- Neutrophils(Complete Blood Count (CBC))
- Lymphocytes(Complete Blood Count (CBC))
- Monocytes(Complete Blood Count (CBC))
- Eosinophils(Complete Blood Count (CBC))
- Basophils(Complete Blood Count (CBC))
- Non-HDL Cholesterol(Lipid Panel / Cardiovascular Health)
- Total Cholesterol/HDL Ratio(Lipid Panel / Cardiovascular Health)
- LDL/HDL Ratio(Lipid Panel / Cardiovascular Health)
- ApoB/ApoA1 Ratio(Lipid Panel / Cardiovascular Health)
- De Ritis Ratio (AST/ALT)(Liver Function)
- Albumin/Globulin Ratio (A/G)(Kidney Function)
- Urine Appearance(Urinalysis)
- Urine Color(Urinalysis)
- Urine pH(Urinalysis)
- Urine Specific Gravity(Urinalysis)
- Urine Protein(Urinalysis)
- Urine Glucose(Urinalysis)
- Urine Ketones(Urinalysis)
- Urine Bilirubin(Urinalysis)
- Urine Blood (Occult)(Urinalysis)
- Urine Nitrite(Urinalysis)
- Urine Leukocyte Esterase(Urinalysis)
- Urine WBC(Urinalysis)
- Urine RBC(Urinalysis)
- Urine Bacteria(Urinalysis)
- Squamous Epithelial Cells (Urine)(Urinalysis)
- Transitional Epithelial Cells (Urine)(Urinalysis)
- Renal Epithelial Cells (Urine)(Urinalysis)
- Hyaline Casts (Urine)(Urinalysis)
- Granular Casts (Urine)(Urinalysis)
- Urine Crystals(Urinalysis)
- Calcium Oxalate Crystals (Urine)(Urinalysis)
- Uric Acid Crystals (Urine)(Urinalysis)
- Triple Phosphate Crystals (Urine)(Urinalysis)
- Yeast (Urine)(Urinalysis)
- Band Neutrophils(Complete Blood Count (CBC))
- Reactive Lymphocytes(Complete Blood Count (CBC))
- Reducing Substances (Urine)(Urinalysis)
Tests Only in SiPhox Health
- Free T3 (Triiodothyronine)(Thyroid Function)
- TPO Antibodies (Thyroid Peroxidase)(Thyroid Function)
- Thyroglobulin Antibodies(Thyroid Function)
- Total Testosterone(Sex Hormones (Male))
- Free Testosterone(Sex Hormones (Male))
- SHBG (Sex Hormone Binding Globulin)(Sex Hormones (Male))
- Estradiol (E2)(Sex Hormones (Male))
- PSA (Prostate Specific Antigen)(Sex Hormones (Male))
- DHEA-S(Sex Hormones (Male))
- Estradiol (E2)(Sex Hormones (Female))
- Progesterone(Sex Hormones (Female))
- FSH (Follicle Stimulating Hormone)(Sex Hormones (Female))
- LH (Luteinizing Hormone)(Sex Hormones (Female))
- Prolactin(Sex Hormones (Female))
- AMH (Anti-Mullerian Hormone)(Sex Hormones (Female))
- Homocysteine(Inflammation &Immune Markers)
- Cortisol(Stress &Adrenal Function)
- Free Androgen Index (FAI)(Additional Specialized Tests)
Complete Biomarker Comparison by Category
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Ready to Choose?
Based on this comparison, make an informed decision about your blood testing provider
Frequently Asked Questions
Which provider is better:Empirical Health or SiPhox Health?
Empirical Health offers better value with 52.6 biomarkers per $100 spent, making it more cost-effective for comprehensive testing.
However, the best choice depends on your specific health goals, budget, and which biomarkers are most important for your situation.
How much do Empirical Health and SiPhox Health cost per year?
Empirical Health costs $190 per year for 1,
while SiPhox Health costs $496 per year for 4.
The cost per test is $190
for Empirical Health and $124
for SiPhox Health.
What biomarkers does Empirical Health test that SiPhox Health doesn't?
Empirical Health includes 55 unique biomarkers not found in SiPhox Health's panel.
These include Hematocrit, Red Blood Cell Count (RBC), White Blood Cell Count (WBC), and others.
Can I use insurance with Empirical Health or SiPhox Health?
Both Empirical Health and SiPhox Health are direct-to-consumer services that typically don't accept insurance.
However, you may be able to submit receipts to your insurance for reimbursement if you have out-of-network benefits,
or use HSA/FSA funds for payment. Check with your insurance provider and the testing companies for specific policies.
How often should I get blood work done?
Most health optimization experts recommend testing 2-4 times per year to establish baselines and track trends.
Empirical Health includes 1 in their annual membership,
while SiPhox Health includes 4.
More frequent testing allows you to track the effectiveness of interventions and catch changes early.
Where can I get blood drawn for these tests?
Empirical Health uses 2200+ locations,
while SiPhox Health uses At-home.
Both typically have thousands of collection centers nationwide. You'll schedule your blood draw through their platform after ordering.
Frequently Asked Questions
Which is cheaper, Empirical Health or SiPhox Health?
Empirical Health is cheaper at $190/year compared to SiPhox Health at $496/year.
Which tests more biomarkers, Empirical Health or SiPhox Health?
Empirical Health tests 100+ biomarkers while SiPhox Health tests 59 biomarkers.
What is Empirical Health best for?
Empirical Health offers 100+ biomarkers for $190/year with 1 test(s) per year. Key features include:Personalized MD video visit included, doctor messaging, custom nutrition plan, exercise routines, mobile app
What is SiPhox Health best for?
SiPhox Health offers 59 biomarkers for $496/year with 4 test(s) per year. Key features include:Needle-free EasyDraw device, AI longevity expert (Sai), wearable integrations (Oura/Fitbit/Apple Watch), supplement recommendations, third-party lab uploads
Which offers better value, Empirical Health or SiPhox Health?
Empirical Health offers better value with approximately 52.6 biomarkers per $100 spent, compared to SiPhox Health's 11.9 biomarkers per $100.