SiPhox Health vs Healthspan

Complete Head-to-Head Comparison

Compare costs, biomarker coverage, and value to find the best blood testing service for your needs

Independent Analysis 2026 Updated Pricing Complete Biomarker Coverage

Quick Comparison Summary

Best Value
SiPhox Health
11.9 biomarkers per $100
Most Comprehensive
Healthspan
70+ biomarkers tested
Most Tests Per Year
SiPhox Health
4 tests/year

Cost & Value Comparison

Service Details

FeatureSiPhox HealthHealthspan
Lab LocationsAt-homeCLIA-certified labs
Key FeaturesNeedle-free EasyDraw device, AI longevity expert (Sai), wearable integrations (Oura/Fitbit/Apple Watch), supplement recommendations, third-party lab uploadsBiological age calculation, rapamycin/acarbose/metformin protocols, GLP-1 protocols, longevity-focused panels
NotesMembership billed per test cycle at $124 (monthly, quarterly or every 6 months - same price per cycle). At the quarterly cadence shown here that is 4 x $124=$496/yr plus shipping. Four core panels included and switchable:Longevity Essentials (25 biomarkers), Thyroid Focus, Hormone Focus, Heart &Metabolic. Ultimate 360 is a paid upgrade at +$125/cycle (59 biomarkers);GLP Monitoring Panel +$75/cycle. At-home needle-free EasyDraw collection. Our 20% affiliate code applies to the first billing cycle only, membership only, excluding shipping and upgrades. HSA/FSA eligible.Model changed from a standalone $349 panel to a $99/month Longevity Optimization membership;the $1,188 shown is that rate annualized, not a figure Healthspan advertises. Core tier includes labs at baseline and 6 months (2/yr) tracking 70+ biomarkers across 9 biological systems;the Advanced tier runs labs quarterly but its price is not published. Includes BioAge+ biological age testing, 1:1 PhD-level coaching and clinician access. Treatment protocols priced separately ($25-$135/mo). Standalone panel pricing is no longer published publicly. Not to be confused with the unrelated myhealthspan.com.

Biomarker Coverage Comparison

43
Tests in Common
5
Only in SiPhox Health
29
Only in Healthspan

Tests Only in SiPhox Health

Tests Only in Healthspan

Complete Biomarker Comparison by Category

Filter by Category

BiomarkerSiPhox HealthHealthspan
Complete Blood Count (CBC)
Hemoglobin
Hematocrit
Red Blood Cell Count (RBC)
White Blood Cell Count (WBC)
Platelet Count
MCV, MCH, MCHC
RDW (Red Cell Distribution Width)
Neutrophils
Lymphocytes
Monocytes
Eosinophils
Basophils
Lipid Panel / Cardiovascular Health
Total Cholesterol
LDL Cholesterol
HDL Cholesterol
Triglycerides
VLDL Cholesterol
Apolipoprotein B (ApoB)
Lipoprotein (a)
LDL Particle Number
LDL Particle Size
Metabolic Health / Glucose
Fasting Glucose
Hemoglobin A1c (HbA1c)
Insulin
Uric Acid
Liver Function
ALT (Alanine Aminotransferase)
AST (Aspartate Aminotransferase)
ALP (Alkaline Phosphatase)
GGT (Gamma-Glutamyl Transferase)
Bilirubin (Total)
Albumin
Total Protein
Globulin
Kidney Function
Creatinine
BUN (Blood Urea Nitrogen)
eGFR (Estimated Glomerular Filtration Rate)
BUN/Creatinine Ratio
Electrolytes &Minerals
Sodium
Potassium
Chloride
Carbon Dioxide (CO2)
Calcium
Thyroid Function
TSH (Thyroid Stimulating Hormone)
Free T4 (Thyroxine)
Free T3 (Triiodothyronine)
TPO Antibodies (Thyroid Peroxidase)
Thyroglobulin Antibodies
Sex Hormones (Male)
Total Testosterone
Free Testosterone
SHBG (Sex Hormone Binding Globulin)
Estradiol (E2)
PSA (Prostate Specific Antigen)
DHEA-S
Sex Hormones (Female)
Estradiol (E2)
Progesterone
FSH (Follicle Stimulating Hormone)
LH (Luteinizing Hormone)
Prolactin
AMH (Anti-Mullerian Hormone)
Inflammation &Immune Markers
hs-CRP (High Sensitivity C-Reactive Protein)
ESR (Erythrocyte Sedimentation Rate)
Homocysteine
Vitamins &Nutrients
Vitamin D (25-Hydroxy)
Vitamin B12
Folate
Ferritin
Iron (Serum)
TIBC (Total Iron Binding Capacity)
Stress &Adrenal Function
Cortisol
Advanced / Specialty Markers
IGF-1 (Insulin-like Growth Factor)
Autoimmune Markers
ANA Screen (Antinuclear Antibodies)
Cancer Screening Markers
Additional Specialized Tests
Neutrophil/Lymphocyte Ratio
LDL-P (LDL Particle Number)
LDL Particle Size Analysis
HDL Subfractions (Large/Small)
Transferrin Saturation
Free Androgen Index (FAI)
Urinalysis
Lipid Panel / Cardiovascular
Pancreas &Digestive

Ready to Choose?

Based on this comparison, make an informed decision about your blood testing provider

Frequently Asked Questions

Which provider is better:SiPhox Health or Healthspan?
SiPhox Health offers better value with 11.9 biomarkers per $100 spent, making it more cost-effective for comprehensive testing. However, the best choice depends on your specific health goals, budget, and which biomarkers are most important for your situation.
How much do SiPhox Health and Healthspan cost per year?
SiPhox Health costs $496 per year for 4, while Healthspan costs $1188 per year for 2. The cost per test is $124 for SiPhox Health and $594 for Healthspan.
What biomarkers does SiPhox Health test that Healthspan doesn't?
SiPhox Health includes 5 unique biomarkers not found in Healthspan's panel. These include TPO Antibodies (Thyroid Peroxidase), Thyroglobulin Antibodies, Vitamin B12, and others.
Can I use insurance with SiPhox Health or Healthspan?
Both SiPhox Health and Healthspan are direct-to-consumer services that typically don't accept insurance. However, you may be able to submit receipts to your insurance for reimbursement if you have out-of-network benefits, or use HSA/FSA funds for payment. Check with your insurance provider and the testing companies for specific policies.
How often should I get blood work done?
Most health optimization experts recommend testing 2-4 times per year to establish baselines and track trends. SiPhox Health includes 4 in their annual membership, while Healthspan includes 2. More frequent testing allows you to track the effectiveness of interventions and catch changes early.
Where can I get blood drawn for these tests?
SiPhox Health uses At-home, while Healthspan uses CLIA-certified labs. Both typically have thousands of collection centers nationwide. You'll schedule your blood draw through their platform after ordering.

Frequently Asked Questions

Which is cheaper, SiPhox Health or Healthspan?

Healthspan is cheaper at $1188/year compared to SiPhox Health at $496/year.

Which tests more biomarkers, SiPhox Health or Healthspan?

SiPhox Health tests 59 biomarkers while Healthspan tests 70+ biomarkers.

What is SiPhox Health best for?

SiPhox Health offers 59 biomarkers for $496/year with 4 test(s) per year. Key features include:Needle-free EasyDraw device, AI longevity expert (Sai), wearable integrations (Oura/Fitbit/Apple Watch), supplement recommendations, third-party lab uploads

What is Healthspan best for?

Healthspan offers 70+ biomarkers for $1188/year with 2 test(s) per year. Key features include:Biological age calculation, rapamycin/acarbose/metformin protocols, GLP-1 protocols, longevity-focused panels

Which offers better value, SiPhox Health or Healthspan?

SiPhox Health offers better value with approximately 11.9 biomarkers per $100 spent, compared to Healthspan's 5.9 biomarkers per $100.

Need More Information?

Get monthly price updates &deals

We track pricing changes across 50+ health testing providers so you don't have to.

Free, once a month. No spam.