TMAO (Trimethylamine N-oxide)
TMAO is produced when gut bacteria metabolize choline, carnitine, and phosphatidylcholine from red meat, eggs, and dairy into TMA, which the liver oxidizes to TMAO. Elevated levels are independently associated with heart attack, stroke, and mortality, and may promote platelet reactivity and foam cell formation. Diet and gut microbiome changes can lower TMAO.
Optimal range: who says what
Institutions, researchers and practitioners draw the line in different places. Each position is listed with who holds it and, where a document states it, a link. How we verify ranges.
- Institution or study<6.2 uMCardiovascular outcome research (Cleveland Clinic cohorts)
- Lab reference intervalNo established lab reference interval (specialty assay)What a lab report flags against. A lab interval is not an optimal target.
1 providers include this
Lipid Panel / Cardiovascular Health
Why TMAO (Trimethylamine N-oxide) matters
Produced by gut bacteria from red meat and eggs. High levels strongly predict heart attack, stroke, and death. Modifiable through diet and gut health optimization.
Which Providers Test TMAO (Trimethylamine N-oxide)?
Of the panels we itemize, only Marek Health Executive ($1950/year, 130+ biomarkers) includes TMAO (Trimethylamine N-oxide).
1 panel that includes it, cheapest first
| Provider | Annual Cost | Total Biomarkers | $/Biomarker |
|---|---|---|---|
| $1950 | 130+ | $15.00 |
$/Biomarker is annual cost divided by the panel's advertised biomarker count, not the price of this one test. We track 23 blood test providers (32 plans); 21 of those plans are itemized marker by marker. Compare all of them.
20 itemized panels do not include TMAO (Trimethylamine N-oxide)
Superpower · WHOOP Advanced Labs · Labcorp OnDemand · Life Extension Elite · Everlywell · Mito Health · InsideTracker · Function Health · Marek Health Base · Marek Health Comprehensive · Marek Health Complete · Blueprint · Empirical Health · Oura Health Panels · SiPhox Health · Hims Labs · Healthspan · Vitality Blueprint Standard · Vitality Blueprint Elite · Ultrahuman Blood Vision Annual
11 providers not itemized in our matrix
We have not itemized these marker by marker (some sell tests one at a time), so this page cannot say whether they offer TMAO (Trimethylamine N-oxide). Check with them directly.
Life Extension Standard · Quest Health · Ultrahuman Blood Vision · Lifeforce · Hundred Health · Personalabs · Walk-In Lab · HealthLabs · WHOOP Specialized Panels · Marek Health Essential · Vitality Blueprint Upload
Frequently Asked Questions
What is the optimal range for TMAO (Trimethylamine N-oxide)?
Published position: <6.2 uM (Cardiovascular outcome research (Cleveland Clinic cohorts)). No established lab reference interval (specialty assay).
Which blood test providers include TMAO (Trimethylamine N-oxide)?
1 of the 21 blood testing panels we itemize marker by marker include TMAO (Trimethylamine N-oxide) in their panels. This biomarker has limited availability.
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Medical Disclaimer
This information is for educational purposes only and is not medical advice. Always consult with a qualified healthcare provider about your specific health needs.
Last reviewed Sep 23, 2026 · First published Nov 30, 2025