Cystatin C
Cystatin C is a small protein produced by all nucleated cells and cleared by glomerular filtration. Because it is largely independent of muscle mass, diet, and sex, it estimates kidney function more accurately than creatinine in elderly, frail, or very muscular individuals. Elevated levels also independently predict cardiovascular events and mortality.
4 providers include this
Kidney Function
0.53-0.95 mg/L
What is Cystatin C?
Cystatin C is a small protein produced by all nucleated cells and cleared by glomerular filtration. Because it is largely independent of muscle mass, diet, and sex, it estimates kidney function more accurately than creatinine in elderly, frail, or very muscular individuals. Elevated levels also independently predict cardiovascular events and mortality.
Why It Matters
More precise measure of kidney filtration, especially useful in elderly, muscular individuals, or those with abnormal creatinine. Better predictor of cardiovascular risk and mortality.
Which Providers Test Cystatin C?
Full Provider Comparison
| Provider | Includes | Annual Cost | Biomarkers |
|---|---|---|---|
 Superpower | — | $199 | 100+ (150 with ratios) |
 WHOOP Advanced Labs | — | $349 | 65 |
 Labcorp OnDemand | — | $398 | 40+ |
| — | $486 | 40+ | |
| — | $449 | 288 | |
| ✓ | $349 | 100+ | |
| — | $829 | 54 | |
 Function Health | ✓ | $365 | 160+ |
| — | $250 | 65 | |
| — | $495 | 80+ | |
| ✓ | $895 | 100+ | |
| ✓ | $1950 | 130+ | |
| — | $375 | 95+ | |
| — | $Varies | 75+ | |
| — | $190 | 100+ | |
| — | $99 | 50 | |
| — | $124 | 60 | |
| — | $349 | 130+ | |
| — | $349 | 80+ | |
| — | $375 | 85 | |
| — | $700 | 128 | |
| — | $99 | 100+ |
Frequently Asked Questions
What is Cystatin C?
Cystatin C is a small protein produced by all nucleated cells and cleared by glomerular filtration. Because it is largely independent of muscle mass, diet, and sex, it estimates kidney function more accurately than creatinine in elderly, frail, or very muscular individuals. Elevated levels also independently predict cardiovascular events and mortality.
What is the optimal range for Cystatin C?
The standard reference range for Cystatin C is 0.53-0.95 mg/L. Optimal ranges may differ based on individual health goals and expert recommendations.
Which blood test providers include Cystatin C?
4 out of 22 blood testing providers include Cystatin C in their panels. This biomarker has limited availability.
What category does Cystatin C fall under?
Cystatin C is categorized under Kidney Function. This category includes biomarkers that help assess related aspects of health and wellness.
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Medical Disclaimer
This information is for educational purposes only and is not medical advice. Always consult with a qualified healthcare provider about your specific health needs.
Last reviewed:2026-04-12