Anion Gap
The anion gap is calculated from sodium, chloride, and bicarbonate and estimates unmeasured anions in blood. A high anion gap suggests metabolic acidosis from conditions such as diabetic ketoacidosis, lactic acidosis, kidney failure, or toxic ingestions (methanol, ethylene glycol, salicylates). A low gap can reflect hypoalbuminemia or lab error.
2 providers include this
Electrolytes &Minerals
8-12 mEq/L
What is Anion Gap?
The anion gap is calculated from sodium, chloride, and bicarbonate and estimates unmeasured anions in blood. A high anion gap suggests metabolic acidosis from conditions such as diabetic ketoacidosis, lactic acidosis, kidney failure, or toxic ingestions (methanol, ethylene glycol, salicylates). A low gap can reflect hypoalbuminemia or lab error.
Why It Matters
High anion gap indicates metabolic acidosis from conditions like diabetic ketoacidosis, lactic acidosis, or kidney failure. Low gap may indicate hypoalbuminemia.
Which Providers Test Anion Gap?
Full Provider Comparison
| Provider | Includes | Annual Cost | Biomarkers |
|---|---|---|---|
 Superpower | ✓ | $199 | 100+ (150 with ratios) |
 WHOOP Advanced Labs | — | $349 | 65 |
 Labcorp OnDemand | ✓ | $398 | 40+ |
| — | $486 | 40+ | |
| — | $449 | 288 | |
| — | $349 | 100+ | |
| — | $829 | 54 | |
 Function Health | — | $365 | 160+ |
| — | $250 | 65 | |
| — | $495 | 80+ | |
| — | $895 | 100+ | |
| — | $1950 | 130+ | |
| — | $375 | 95+ | |
| — | $Varies | 75+ | |
| — | $190 | 100+ | |
| — | $99 | 50 | |
| — | $124 | 60 | |
| — | $349 | 130+ | |
| — | $349 | 80+ | |
| — | $375 | 85 | |
| — | $700 | 128 | |
| — | $99 | 100+ |
Frequently Asked Questions
What is Anion Gap?
The anion gap is calculated from sodium, chloride, and bicarbonate and estimates unmeasured anions in blood. A high anion gap suggests metabolic acidosis from conditions such as diabetic ketoacidosis, lactic acidosis, kidney failure, or toxic ingestions (methanol, ethylene glycol, salicylates). A low gap can reflect hypoalbuminemia or lab error.
What is the optimal range for Anion Gap?
The standard reference range for Anion Gap is 8-12 mEq/L. Optimal ranges may differ based on individual health goals and expert recommendations.
Which blood test providers include Anion Gap?
2 out of 22 blood testing providers include Anion Gap in their panels. This biomarker has limited availability.
What category does Anion Gap fall under?
Anion Gap is categorized under Electrolytes &Minerals. This category includes biomarkers that help assess related aspects of health and wellness.
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Medical Disclaimer
This information is for educational purposes only and is not medical advice. Always consult with a qualified healthcare provider about your specific health needs.
Last reviewed:2026-04-12