Signos vs Zoe

CGM Head-to-Head Comparison

Compare pricing, sensor technology, app features, and coaching support to find the best CGM for your goals

Signos
Signos
Independent Analysis January 2026 Pricing Feature-by-Feature Comparison

Quick Comparison Summary

Best Value
Zoe
Lower monthly cost
Best Accuracy
Signos
Lower MARD%
Best Support
Signos
Better coaching
Longest Wear Time
Signos
Longer sensor life

Pricing & Plans Comparison

Sensor Technology

SpecificationSignosZoe
Sensor TypeDexcom SteloN/A - no CGM
Accuracy (MARD)9.0%N/A
Reading FrequencyEvery 5 minN/A
Warm-up Time30 minN/A
Wear Time15 daysN/A
Water Resistance8ft/24hrN/A

App Features & Coaching

FeatureSignosZoe
Coaching Type✓ 1:1 DietitianAI nutrition coach (AskZiggie)
Food LoggingPhoto + manual loggingPhoto + manual + barcode scanning
Scoring SystemWeight loss score + meal scoresZOE score (0-100) per food
App IntegrationsApple Health, Google Health Connect, Garmin Connect, Oura, Whoop, Fitbit, Samsung Health, Google Fit, MyFitnessPal, PelotonApple Health
Prescription RequiredNot requiredNot required
HSA/FSA EligibleNoNo

Key Features

Signos

Best for: Weight loss seekers wanting GLP-1 support and dietitian access

Key features: Real-time glucose tracking, AI meal insights, exercise recommendations, weight loss tools, GLP-1 integration support, in-app dietitian chat, Apple Watch integration

Not recommended for: Insulin users, active cancer treatment, eating disorders

Zoe

Best for: Those prioritizing gut microbiome health and AI-powered nutrition over real-time glucose

Key features: Gut microbiome analysis, AI food tracking with photo logging, Processed Food Risk Scale, plant diversity counter, personalized food scoring

Not recommended for: Those wanting CGM tracking

Signos Details

FDA-cleared for weight management (Aug 2025). Uses Dexcom Stelo sensors. Tiers:3-month ($139/mo), 6-month ($129/mo). Maintenance Plan:$75/mo for existing members. Dietitian sessions via Nourish partnership (94% pay $0).

Zoe Details

US:$294 test kit + $9.99-24.99/mo. Core plan:$414/yr total. Jan 2026 update:simplified next-gen test no longer includes CGM or blood tests - uses gut microbiome only with predictive algorithms. UK-based. Not available in NY.

Ready to Choose?

Based on this comparison, select the CGM service that best fits your health goals

Frequently Asked Questions

Which is better:Signos or Zoe?
Signos is best for weight loss seekers wanting glp-1 support and dietitian access, while Zoe is ideal for those prioritizing gut microbiome health and ai-powered nutrition over real-time glucose. Zoe is more affordable at $10/month compared to Signos's $129/month. The best choice depends on your specific health goals and budget.
How much do Signos and Zoe cost?
Signos costs $129/month ($1548/year), while Zoe costs $10/month ($414/year). Both services are HSA/FSA eligible.
Which CGM sensor is more accurate?
Signos uses Dexcom Stelo with 9.0% MARD, while Zoe uses N/A - no CGM with N/A MARD. Lower MARD indicates better accuracy. Both are considered highly accurate for wellness purposes.
Do I need a prescription for Signos or Zoe?
Neither Signos nor Zoe requires a prescription. Both are available over-the-counter.
Which has better coaching support?
Signos includes 1:1 registered dietitian support, while Zoe offers AI nutrition coach (AskZiggie).
Can I use Signos or Zoe for weight loss?
Signos is specifically designed for weight loss. CGMs help identify which foods spike your blood sugar, enabling dietary changes that support weight loss without medication.

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