Shield by Guardant vs Cologuard by Exact Sciences

Side-by-side comparison of cancer screening tests.

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Shield by Guardant

FDA approved
$895

Colorectal only

Cologuard by Exact Sciences

FDA approved
$649

Colorectal only

Test Performance

FeatureShield by GuardantCologuard by Exact Sciences
Price$895$649
Cancers DetectedColorectal onlyColorectal only
Sensitivity84% for CRC92% for CRC
Specificity90%87%
Sample TypeBlood drawStool sample
FDA StatusFDA approvedFDA approved